MytuD.01649.a: Putative conserved protein Rv2377c; MbtH
Target Characteristics
| from organism: | Mycobacterium tuberculosis H37Rv |
| most recent status: | in PDB |
| center reference id: | MytuD.01649.a |
| is community request: | True |
| associated disease: | Tuberculosis |
| NIH risk group: | 2 |
| is select agent: | False |
| NIH priority pathogens category: |
IIIC |
Ordering Clones & Proteins
If there are materials available for this target, they will be listed below.
Materials can be ordered from SSGCID using the button in the "order material" column.
Clicking the button will add the material to a virtual cart.
You may order multiple materials at a time at no cost to you, as this contract is funded
by NIAID. When you are ready to place your order, click the "Place Order" link which will
appear in the top right corner of the page after you place your first item in your cart.
Structures
2KHR
Deposited: 4/10/2009
Determination: NMR
Clone: MytuD.01649.a.M1.GE00001
Protein: MytuD.01649.a.M1.PB00023
Publications by SSGCID
Solution structure of Rv2377c-founding member of the MbtH-like protein family.
Buchko GW, Kim CY, Myler PJ, Terwilliger TC
Tuberculosis (Edinb) - 2010
volume 90, issue 4, pages 245-51
PMID: 20434955; PMCID: PMC2910232
PDB:
2KHR
External Resources
| Resource | Reference ID |
|---|---|
| OrthoMCL: | OG5_160502 |
| PATRIC ID: | fig|83332.12.peg.2658 |
| RefSeq: | NP_216893.1 |
| TubercuList: | Rv2377c |
| MTB Network Portal: | Rv2377c |
| UniProt: | P9WIP5 |
Orthologues for Rv2377c
| Species | % Identity | % Coverage | Clones | Proteins | Structures |
|---|---|---|---|---|---|
| avium | 78 | 97 | 1 | 1 | 0 |
| avium | 78 | 97 | 1 | 1 | 1 |
| smegmatis | 78 | 96 | 1 | 1 | 0 |
| marinum | 76 | 100 | 0 | 0 | 0 |
| smegmatis | 76 | 99 | 1 | 0 | 0 |
| thermoresistibile | 76 | 99 | 0 | 0 | 0 |
| ulcerans | 75 | 100 | 0 | 0 | 0 |
| abscessus | 74 | 99 | 0 | 0 | 0 |
| thermoresistibile | 74 | 99 | 0 | 0 | 0 |
| ulcerans | 72 | 100 | 0 | 0 | 0 |
| marinum | 72 | 96 | 1 | 1 | 1 |
| avium | 71 | 96 | 1 | 0 | 0 |
| paratuberculosis | 71 | 96 | 1 | 0 | 0 |
| marinum | 70 | 100 | 0 | 0 | 0 |
| abscessus | 70 | 99 | 0 | 0 | 0 |
| marinum | 70 | 97 | 0 | 0 | 0 |
| abscessus | 69 | 96 | 1 | 1 | 0 |
| marinum | 68 | 96 | 0 | 0 | 0 |
| smegmatis | 63 | 94 | 0 | 0 | 0 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSTNPFDDDN GAFFVLVNDE DQHSLWPVFA DIPAGWRVVH GEASRAACLD YVEKNWTDLR PKSLRDAMVE D
NT Sequence
gtgagcacca atcctttcga tgacgacaac ggcgcattct tcgtgctggt caacgacgaa gaccagcaca gcctgtggcc ggtgttcgcc gatatcccgg ccggctggcg cgtggtgcac ggcgaagcca gccgtgccgc ctgcctggac tacgtggaaa agaactggac cgatctgcgg ccgaagagcc tgcgtgacgc catggtcgag gactga