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Seattle Structural Genomics Center for Infectious Disease

TrcrA.01024.a: enolase

Target Characteristics

from organism: Trypanosoma cruzi
most recent status: in PDB
center reference id: TrcrA.01024.a
is community request: True
associated disease:
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
unclassified

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
TrcrA.01024.a.B1.GE35134 full length 1 429 GE35134
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
TrcrA.01024.a.B1.PW35751 full length 1 429

Structures

image of structure for 4G7F
4G7F
Deposited: 7/20/2012
Determination: XRay
Diffraction Image
Clone: TrcrA.01024.a.B1.GE35134
Protein: TrcrA.01024.a.B1.PW35751

External Resources

Resource Reference ID
EuPathDB: TritrypDB:Tc00.1047053504105.140
OrthoMCL: OG5_126698
RefSeq: XP_819700.1
UniProt: Q4DZ98

Enzyme & Pathway Information

Pathway Pathway ID EC Number
homolactic fermentation ANAEROFRUCAT-PWY 4.2.1.11
glycolysis III (from glucose) ANAGLYCOLYSIS-PWY 4.2.1.11
respiration (anaerobic) ANARESP1-PWY 4.2.1.11
gluconeogenesis I GLUCONEO-PWY 4.2.1.11
glycolysis I (from glucose 6-phosphate) GLYCOLYSIS 4.2.1.11
superpathway of glycolysis and the Entner-Doudoroff pathway GLYCOLYSIS-E-D 4.2.1.11
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass GLYCOLYSIS-TCA-GLYOX-BYPASS 4.2.1.11
superpathway of hexitol degradation (bacteria) HEXITOLDEGSUPER-PWY 4.2.1.11
Entner-Doudoroff pathway II (non-phosphorylative) NPGLUCAT-PWY 4.2.1.11
heterolactic fermentation P122-PWY 4.2.1.11
Bifidobacterium shunt P124-PWY 4.2.1.11
glycolysis V (Pyrococcus) P341-PWY 4.2.1.11
superpathway of N-acetylneuraminate degradation P441-PWY 4.2.1.11
hexitol fermentation to lactate, formate, ethanol and acetate P461-PWY 4.2.1.11
glycolysis IV (plant cytosol) PWY-1042 4.2.1.11
formaldehyde assimilation I (serine pathway) PWY-1622 4.2.1.11
Entner-Doudoroff pathway III (semi-phosphorylative) PWY-2221 4.2.1.11
superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle PWY-5464 4.2.1.11
glycolysis II (from fructose 6-phosphate) PWY-5484 4.2.1.11
Rubisco shunt PWY-5723 4.2.1.11
gluconeogenesis II (Methanobacterium thermoautotrophicum) PWY-6142 4.2.1.11
Methanobacterium thermoautotrophicum biosynthetic metabolism PWY-6146 4.2.1.11
gluconeogenesis III PWY66-399 4.2.1.11
glycolysis VI (metazoan) PWY66-400 4.2.1.11
1-butanol autotrophic biosynthesis (engineered) PWY-6886 4.2.1.11
superpathway of glucose and xylose degradation PWY-6901 4.2.1.11
glycerol degradation to butanol PWY-7003 4.2.1.11
ethylene biosynthesis V (engineered) PWY-7124 4.2.1.11
photosynthetic 3-hydroxybutanoate biosynthesis (engineered) PWY-7218 4.2.1.11
superpathway of anaerobic sucrose degradation PWY-7345 4.2.1.11

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MTIQKVHGRE ILDSRGNPTV EVEVTTELGV FRSAVPSGAS TGIHEACELR DDDKRRYLGK GCLNAVKNVN DVLAPALVGK DELQQSTLDK LMRDLDGTPN KSKLGANAIL GCSMAISKAA AARKGVPLYR YLAELAGTKE VRLPVPCFNV INGGKHAGNA LPFQEFMIAP VKAGSFNEAL RMGAEVYHSL KSIIKKKYGQ DAVNVGDEGG FAPPITDINE PLPILMEAIE QAGHKGRFAI CMDSAASETY DENKKQYNLT FKSPEATWVT AKQLAETYAK WVSEYPIVSL EDPYDQDDFD GFAGITEALK GKAQVVGDDL TVTNVSRIKT AIEKKACNSL LLKINQIGTI TEAIEASKFC MSNGWSVMVS HRSGETEDTY IADLVVGLGT GQIKTGAPCR GERTAKLNQL LRIEEELGAH AKFGFPAWS

NT Sequence
atgacaatcc aaaaggttca cggacgcgag attcttgact cgcgtggaaa ccccactgtt gaggtagagg taacgacgga actgggcgtg ttccgctccg ccgttccgtc cggtgcgtcg accggcatcc acgaggcatg cgagctgcgc gatgatgaca agaggcgcta cctgggcaag ggctgcctca atgcggtgaa gaatgtgaac gatgtcctgg cgcccgcact tgtgggcaaa gacgagctgc agcagtcgac gctggacaag ctgatgcgtg accttgacgg gacaccaaac aagagcaaac ttggcgcaaa cgccattctc ggctgctcga tggcgatcag caaggcagcg gcggctcgca agggcgttcc gctgtaccgt tacctggcag agctggccgg cacaaaggag gttcgtcttc ccgtgccttg cttcaacgtc atcaacggtg gcaagcacgc gggcaacgcg ttgcccttcc aggaatttat gattgctcca gtgaaggcag gctctttcaa cgaggcgctg cgcatgggtg cggaggtgta tcactcgctg aagagcatca tcaagaagaa gtacggccag gatgcggtga acgtgggcga cgagggtggc tttgctcctc caatcacgga catcaatgag ccgctgccga ttctcatgga ggcgattgaa caggctggac acaagggcag gtttgctatc tgcatggact ccgctgccag tgagacatat gacgagaaca agaagcagta caacctgacc ttcaagagcc ctgaagcgac ctgggtgacg gcgaagcagc tggccgagac ttacgccaaa tgggtgagcg agtaccctat tgtgagcctc gaggaccctt acgaccagga cgactttgat ggctttgccg gcatcacgga ggctctcaag ggcaaggctc aggtcgtcgg tgacgactta actgtgacga atgtgtcacg catcaaaacg gccattgaga agaaggcatg caactcgctg ctgcttaaga tcaaccagat cggtacgatc acggaggcca tcgaggcatc caagttctgc atgtcgaacg gctggtcggt gatggtgtcg caccgcagtg gtgagacgga ggacacgtac attgctgacc ttgtggtggg cctcggcact ggccagatca agacgggcgc gccgtgccgt ggcgagcgca ccgcaaaact gaaccagcta ctccgcatcg aagaagagct tggtgcacac gccaagttcg gcttccccgc atggtcgtag

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