TogoA.17087.a
delta-aminolevulinic acid dehydratase
| CENTER ID: | TogoA.17087.a |
| ORGANISM: | Toxoplasma gondii ME49 |
| ASSOCIATED DISEASE: | Toxoplasmosis |
| CURRENT STATUS: | in PDB |
| COMMUNITY REQUEST: | True |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | False |
| NIH PRIORITY pathogens category: |
IIIB |
Ordering Clones & Proteins
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Structures
3OBK
DEPOSITED: 8/6/2010
DETERMINATION: XRay
CLONE:
PROTEIN: TogoA.17087.a.Y2.PC0001
Publications by SSGCID
Crystal structure of Toxoplasma gondii porphobilinogen synthase: insights on octameric structure and porphobilinogen formation.
Dieterich S, Gardberg A, Jaffe EK, Myler PJ, Roos DS, Sankaran B, Shanmugam D, Stewart LJ
J. Biol. Chem. - 2011
volume 286, issue 17, pages 15298-307
PMID: 21383008; PMCID: PMC3083160
PDB:
3OBK
External Resources
| RESOURCE | REFERENCE ID |
|---|---|
| EuPathDB: | ToxoDB:TGME49_253900 |
| OrthoMCL: | OG5_127486 |
| RefSeq: | XP_002369445.1 |
| UniProt: | B6KNM2 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
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AA Sequence
MRPLSLFFRL SFLLFVLLFP SPSVDALLQS SSVAGSFPTP ASVASSGRSV SPHNALYVHS RTEATAGLPS GASLAITLNG ESEEPRRNGA RRKGSKSLGF LVAPPLSRSC TTEQTGELFS GGAKVRGLNV QVTASPVGRE LASSLRSRAS EPEIRQLAAS PIFGAPKPFS SCPCSSSSRS SCAAHPSALL PEVCSFVSRR GARRNLGAQR GRGPGARGQR LGAAAGPTPV GKGTPGGAKG QFRGGMSAQK GAVHQEPLRG RLEEDEEEED EFEDDEFDDE DEGEDEGEDE EYDEEDDEDY DPMTPRGPLD NNNYGEVWLP IQARPRRNRK NRAVRQLVQE NLVKPSSLIY PLFVHDEETS VPIPSMPGQS RLSMEDLLKE VGEARSYGIK AFMLFPKVDD ELKSVMAEES YNPDGLLPRA IMALKEAFPD VLLLADVALD PYSSMGHDGV VDEQSGKIVN DLTVHQLCKQ AITLARAGAD MVCPSDMMDG RVSAIRESLD MEGCTDTSIL AYSCKYASSF YGPFRDALDS HMVGGTDKKT YQMDPSNSRE AEREAEADAS EGADMLMVKP GLPYLDVLAK IREKSKLPMV AYHVSGEYAM LKAAAEKGYI SEKDTVLEVL KSFRRAGADA VATYYAKEAA KWMVEDMKGT QKFTEPCY
NT Sequence
atgcgtcctc tctcgctttt cttccgactt tccttcctct tgttcgtcct tctcttcccg tctccctctg tcgacgcgct cctccagtct tcctcagtcg cgggttcctt tcctacgcca gcttcggtgg cttcttccgg tcgttctgtc tcgccgcaca acgcgctgta cgtacactcc aggactgagg cgactgcggg gctgccctcc ggagcttctc tcgctatcac cctgaatggg gaaagcgaag aaccacgtag aaatggtgca aggaggaagg gatctaagtc cctaggtttc ctcgtcgcgc ctcctctttc gcggagctgt accacggagc agaccggaga gcttttctcc ggaggagcga aggttcgcgg gttaaatgtc caggtcactg cgtcgcccgt cggtcgcgaa ctcgcttctt ctctccggtc gcgtgcatcg gaacctgaaa ttcgacaact cgctgcgtcg ccgatcttcg gtgctcccaa gccgttctct tcctgtccgt gttcgtcctc gtctcgttcc tcttgtgctg cgcatcctag tgcgctgctg cctgaggtct gttccttcgt gtctcgccgc ggagcccgaa gaaatctcgg agcccaacgc ggtcgcgggc ctggggcgcg gggccagcgc ctcggggccg cggcgggtcc gacgccggtg gggaagggaa cacccggcgg ggcgaagggt cagttcagag gcgggatgag tgcgcagaag ggagcggtgc atcaagagcc gctccgaggc cgccttgagg aagacgaaga ggaagaggac gagttcgaag acgatgagtt cgatgacgaa gacgagggcg aagacgaggg cgaagacgag gaatacgatg aggaggatga tgaggactac gatccgatga cgccacgggg gcccctcgac aacaacaact acggcgaggt ctggcttccc attcaagcac gccctcgaag aaaccggaaa aaccgcgccg ttcgccaact cgtccaggaa aacctcgtca aaccttcgag tctcatctat cctctttttg tccacgacga agaaacgagt gtgccgattc cctcgatgcc tggccaaagt cgtctgagca tggaagatct gttgaaggag gtgggcgagg cccgaagcta cggcatcaaa gcgttcatgc tcttcccgaa agtcgatgac gaactcaaat cagtcatggc cgaagaaagc tacaatccgg acggcctctt gcctcgcgcc ataatggctc tgaaggaagc tttcccagat gtccttctcc tggcagatgt ggctcttgac ccatacagct ctatgggtca cgatggcgtt gtcgatgaac aaagcggaaa gatcgtaaac gatcttactg ttcaccagct gtgcaaacag gcgattacgc ttgcgcgcgc aggggcagat atggtgtgtc cgagtgatat gatggacgga cgtgtgtcgg cgattcggga gtctctcgac atggaaggtt gcacagacac cagcattctc gcctactcct gcaaatacgc ctcctcgttc tatggcccgt tccgcgatgc tctggactca cacatggttg gcggcacaga caagaaaaca tatcagatgg acccgtcgaa ctcccgcgaa gcagagagag aagccgaagc agacgcctct gaaggcgcgg acatgctgat ggtgaagccg gggctcccgt atctggatgt attggcaaag attcgcgaga agtcgaaact gcccatggtg gcttaccacg tttcgggaga atatgctatg ctcaaagccg cggcggagaa gggctacatc agtgagaagg atacggtcct ggaagtcctc aagagcttcc gacgcgcggg tgcagacgcc gtggccacct actacgccaa agaggcggcc aaatggatgg tcgaggacat gaaaggaacg cagaagttta cagaaccctg ctactaa