NIAID Emerging and Re-emerging Infectious Diseases NIAID Bioinformatics Resource Centers NIAID Structural Genomic Centers Center for Structural Genomics of Infectious Disease
Seattle Structural Genomics Center for Infectious Disease

MytuD.18400.a: Putative uncharacterized protein

Target Characteristics

from organism: Mycobacterium tuberculosis H37Rv
most recent status: in PDB
center reference id: MytuD.18400.a
is community request: True
associated disease: Tuberculosis
NIH risk group: 2
is select agent: False
NIH priority
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.18400.a.A1.GE34391 full length 1 168 GE34391
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
MytuD.18400.a.A1.PS02520 full length 1 168

Structures

image of structure for 4HEC
4HEC
Deposited: 10/3/2012
Determination: XRay
Diffraction Image
Clone: MytuD.18400.a.A1.GE34391
Protein: MytuD.18400.a.A1.PS01434
image of structure for 4HVJ
4HVJ
Deposited: 11/6/2012
Determination: XRay
Diffraction Image
Clone: MytuD.18400.a.A1.GE34391
Protein: MytuD.18400.a.A1.PS01434

Publications by SSGCID

Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution.
Abendroth J, Andrews ES, Arcus VL, Edwards TE, Grundner C, Myler PJ, Ollodart A, Staker BL
J. Biol. Chem. - 2013
volume 289, issue 4, pages 2139-47
PMID: 24311791; PMCID: PMC3900960
PDB: 4HEC, 4HVJ

External Resources

Resource Reference ID
OrthoMCL: OG5_237628
PATRIC ID: fig|83332.12.peg.2430
RefSeq: NP_216695.1
TubercuList: Rv2179c
MTB Network Portal: Rv2179c
UniProt: P9WJ73

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MRYFYDTEFI EDGHTIELIS IGVVAEDGRE YYAVSTEFDP ERAGSWVRTH VLPKLPPPAS QLWRSRQQIR LDLEEFLRID GTDSIELWAW VGAYDHVALC QLWGPMTALP PTVPRFTREL RQLWEDRGCP RMPPRPRDVH DALVDARDQL RRFRLITSTD DAGRGAAR

NT Sequence
gtgcggtact tctacgacac cgaattcatc gaggatgggc acaccatcga gttgatctcg atcggggtgg tcgcagaaga cggccgcgaa tactacgcag tatccacgga attcgatccc gagcgggccg gcagctgggt gcgcacccat gtgctgccca agctgccgcc gcccgcctcg caactgtggc gctcgcgcca gcagattcgt cttgacctgg aagaattcct ccgcatcgac ggcacggatt cgatcgagtt gtgggcctgg gtgggggcct acgaccatgt agcgctgtgt caattgtggg gcccgatgac tgccttgcca cccacagtgc cccgtttcac ccgggaactg cggcagttgt gggaggaccg gggatgcccc cggatgccgc cgcggccacg cgacgtccac gacgcgctgg tcgatgcccg agatcagctg cgccggtttc gtctcatcac gtccacagac gatgcgggcc gcggcgcggc ccgctga

© 2023 Seattle Children's Research Institute. All rights reserved.