LeinA.00674.a
Tyrosine aminotransferase
| CENTER ID: | LeinA.00674.a |
| ORGANISM: | Leishmania infantum |
| ASSOCIATED DISEASE: | Visceral leishmaniasis |
| CURRENT STATUS: | in PDB |
| COMMUNITY REQUEST: | True |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | False |
| NIH PRIORITY pathogens category: |
unclassified |
Ordering Clones & Proteins
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Structures
4IX8
DEPOSITED: 1/24/2013
DETERMINATION: XRay
CLONE: LeinA.00674.a.BV2.GE00001
PROTEIN: LeinA.00674.a.BV2.PC00092
Publications by SSGCID
Structure of tyrosine aminotransferase from Leishmania infantum.
Abendroth J, Abramov A, Alcolea PJ, Alonso A, Edwards T, Larraga V, Lorimer D, Moreno MA, Myler PJ, Zhang S
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. - 2014
volume 70, issue Pt 5, pages 583-7
PMID: 24817714; PMCID: PMC4014323
PDB:
4IX8
Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate.
Abendroth J, Abramov A, Alcolea PJ, Alonso A, de Lacoba MG, Edwards T, Larraga V, Lorimer D, Moreno MA, Myler PJ, Zhang S
Int. J. Parasitol. - 2014
volume 4, issue 3, pages 347-54
PMID: 25516846; PMCID: PMC4266777
PDB:
4IX8
External Resources
| RESOURCE | REFERENCE ID |
|---|---|
| EuPathDB: | TritrypDB:LinJ.36.2490 |
| RefSeq: | XP_001469829.1 |
| UniProt: | A4IDL0 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MTIDTQAAPA AQTLKAGNST GSLTEERREV EQQRAAENTS FRRIASSKHA QRTLQPLNNL TDNMKPSRST KSNLRLSIGD PTVDGNLKTP DIVTEAMVDV VRSGKFNGYP PTVGADNLRQ VVSTYWRRFC QTKSRQEALK WENVIITSGV SQAIVLALTA LCNEGDNILV CAPSFPHYKS VCDSYGIECR YYYLDPSKSW ECDLRAAAGM VDSHTKAFVI INPSNPCGSN FSRAHVSDII DFCQQHQIPL ISDEIYAEMV LNNGIFTSVA DFDTNVPRLI LGGTAKYQVC PGWRVGWSIL IDPMNVAGDW AVGMERLTQL IAGVNSICQE AIARTLLKCP TECTEHIVTQ LEAGAKVYAR LLEHDIGISM EAPQASMFVM LKLNLSYFQD LKSDMEFYEK LLDEENVQVL PGEIFGMSGF LRATVSRPSA VLNEAVDRII EFCERHKK
NT Sequence
atgacgattg atacgcaggc cgcacccgct gctcaaacct tgaaggccgg caactccaca ggatctctca ccgaggagcg ccgcgaggtc gagcagcagc gcgcagctga gaacacgagt tttcgccgta tcgcgtcctc gaagcacgcc cagcgaaccc tgcagccgtt gaacaacttg accgacaaca tgaagccttc ccgctccact aagtcgaact tgcgtctctc catcggcgac cccactgtcg acggcaatct aaagaccccc gacattgtaa cagaggcaat ggtagatgta gtgcgctctg gcaagttcaa cggctacccg ccgacggtcg gggcagacaa cttgcgccag gtggtgtcga cctactggcg ccgcttctgc cagaccaagt ctcgtcaaga ggcgttgaag tgggagaacg tgatcatcac gtccggtgtg tcgcaggcca tcgtgctcgc tctcacggca ctgtgcaacg agggcgacaa catcctcgtg tgcgccccat cgtttcccca ctacaagagc gtctgcgaca gctacggcat cgagtgccgc tactattacc tcgacccctc gaagagctgg gagtgcgacc tcagagctgc ggccggtatg gtggatagcc acaccaaggc atttgtcatc atcaacccct ccaacccgtg cggcagcaac ttctcccgtg cacacgtgag cgatatcatc gatttctgcc agcagcacca gatcccactc atcagtgacg aaatctacgc tgagatggtg ctgaacaacg gcatcttcac gtctgtcgcc gacttcgaca cgaacgttcc gcgtctcatc ctgggcggca cagccaagta tcaggtctgc cccggctggc gcgtaggctg gtctattctg atcgacccaa tgaacgttgc gggagactgg gctgtcggaa tggagcgact gacccagctc atcgctggcg tcaactctat ctgccaggag gcgattgcgc ggacactgct caagtgcccg acggagtgca ccgagcacat cgtcactcaa ctggaggccg gcgccaaagt gtacgcccga ctgctcgaac acgacattgg catctccatg gaggcgccgc aggcctccat gttcgtgatg ctcaagctga acctcagcta ctttcaggat ttgaagtcgg acatggagtt ctacgagaaa ctgctggatg aggagaacgt gcaggtgctg ccgggtgaga tctttggcat gagtggcttc cttcgtgcaa cggtttcccg cccatcggcg gtgctgaatg aggcagtcga ccgcatcatc gagttctgcg agcgccacaa gaagtag