KlpnA.17987.a
DNA polymerase III, beta subunit; beta sliding clamp
| CENTER ID: | KlpnA.17987.a |
| ORGANISM: | Klebsiella pneumoniae |
| ASSOCIATED DISEASE: | Pneumonia |
| CURRENT STATUS: | in PDB |
| COMMUNITY REQUEST: | True |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | False |
| NIH PRIORITY pathogens category: |
unclassified |
Ordering Clones & Proteins
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Structures
6P81
DEPOSITED: 6/6/2019
DETERMINATION: XRay
CLONE: KlpnA.17987.a.EN11.GE42932
PROTEIN: KlpnA.17987.a.EN11.PD38352
Publications by SSGCID
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens
Abendroth JA, Barrett L, Choi R, Dranow DM, Edwards TE, Hewitt SN, Lorimer DD, Myler PJ, Phan IQ, Pierce PG, Staker BL, Subramanian S, Udell HS, Van Voorhis W, Wallace E, Mayclin SJ, Hammerson B, Chun IKH, Barrett KF, Conrady DG, Mueller R, Tillery L, Lukat P, Blankenfeldt W, Higgins T, Bowatte K, Smutney H, Stigliano M, Fenwick MK, Craig J, Peng V, DeRocher AE
Nat Commun - 2024
volume 7, issue 1,
PMID: 39639052; PMCID: PMC11621423
External Resources
| RESOURCE | REFERENCE ID |
|---|---|
| UniProt: | W1BGQ6 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MKFTVEREHL LKPLQQVSGP LGGRPTLPIL GNLLLQVADG TLSLTGTDLE MEMVARVALV QPHEPGATTV PARKFFDICR GLPEGAEIAV QLEGERMLVR SGRSRFSLST LPAADFPNLD DWQSEVEFTL PQATMKRLIE ATQFSMAHQD VRYYLNGMLF ETEGEELRTV ATDGHRLAVC SMPIGQSLPS HSVIVPRKGV IELMRMLDGG DNPLRVQIGS NNIRAHVGDF IFTSKLVDGR FPDYRRVLPK NPDKHLEAGC DLLKQAFARA AILSNEKFRG VRLYVSENQL KITANNPEQE EAEEILDVTY SGAEMEIGFN VSYVLDVLNA LKCENVRMML TDSVSSVQIE DAASQSAAYV VMPMRL
NT Sequence
atgaaattta ccgtagaacg tgagcattta ttaaaaccgc tacaacaggt gagcggtccg ttaggtggtc gtcctacgct accgattctc ggtaatctgc tgttacaggt tgctgacggt acgttgtcgc tgaccggtac tgatctcgag atggaaatgg tggcacgtgt tgcgctggtt cagccacacg agccaggagc gacgaccgtt ccggcgcgca aattctttga tatctgccgt ggtctgcctg aaggcgcgga aattgccgtg cagctggaag gtgaacggat gctggtacgc tccgggcgta gccgtttttc gctgtctacc ctgccagcgg cggatttccc gaacctcgat gactggcaga gtgaagtcga atttaccctg ccgcaggcaa cgatgaagcg tctgattgaa gcgacccagt tttctatggc gcatcaggac gttcgctatt acttaaatgg tatgctgttt gaaaccgaag gtgaagaact gcgcaccgtg gcaaccgacg gccaccgtct ggcggtctgt tcaatgccaa ttggtcaatc tttgccaagc cattcggtga tcgtaccgcg taaaggcgtg attgaactga tgcgtatgct cgacggcggc gacaatccgc tgcgcgtaca gattggcagc aacaacattc gcgcccacgt tggcgacttt atcttcacct ccaaactggt ggatggtcgc ttcccggatt atcgccgcgt tctgccgaag aacccggaca aacatctgga agctggctgc gatctgctca agcaggcgtt tgctcgcgcg gcgattctct ctaacgagaa attccgcggc gtacgtcttt atgtcagcga aaaccagctg aaaatcaccg ccaacaaccc ggaacaggaa gaagcggaag agatcctcga cgttacctat agcggtgcgg agatggaaat cggcttcaac gtcagttatg tgctggatgt tctgaacgcg ctgaaatgcg aaaacgtccg catgatgctg accgattcgg tttccagcgt gcagattgaa gatgcggcca gccagagcgc ggcttatgtt gtcatgccaa tgagactgta a