InvcI.18715.a
Hemagglutinin (HA)
| CENTER ID: | InvcI.18715.a |
| ORGANISM: | Influenzavirus A Influenza A virus A/X-6 COBRA wt rHA (H1N1) (synthetic) |
| ASSOCIATED DISEASE: | |
| CURRENT STATUS: | purified |
| COMMUNITY REQUEST: | True |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | False |
| NIH PRIORITY pathogens category: |
IIIC |
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Structures
8F38
DEPOSITED: 11/9/2022
DETERMINATION: CryoEM
CLONE: InvcI.18715.a.K1.GE43026
PROTEIN: InvcI.18715.a.K1.PC00168
8GHK
DEPOSITED: 3/10/2023
DETERMINATION: CryoEM
CLONE: InvcI.18715.a.K1.GE43026
PROTEIN: InvcI.18715.a.K1.PC00168
Publications by SSGCID
Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6
Abendroth J, Edwards TE, Yang M, Mousa JJ, Nagashima KA, Sautto GA, Dzimianski JV, Ross TM, DuBois RM
Structure - 2024
volume 32, issue 8, pages 1079-1089.e6
PMID: 38810648; PMCID: PMC11316637
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
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AA Sequence
MKAILVVLLY TFATANADTL CIGYHANNST DTVDTVLEKN VTVTHSVNLL EDKHNGKLCK LRGVAPLHLG KCNIAGWILG NPECESLSTA SSWSYIVETP SSDNGTCYPG DFIDYEELRE QLSSVSSFER FEIFPKTSSW PNHDSNKGVT AACPHAGAKS FYKNLIWLVK KGNSYPKLSK SYINDKGKEV LVLWGIHHPP TSADQQSLYQ NADAYVFVGS SRYSKKFKPE IAIRPKVRDQ EGRMNYYWTL VEPGDKITFE ATGNLVVPRY AFAMERNAGS GIIISDTPVH DCNTTCQTPK GAINTSLPFQ NIHPITIGKC PKYVKSTKLR LATGLRNIPS IQSRGLFGAI AGFIEGGWTG MVDGWYGYHH QNEQGSGYAA DLKSTQNAID EITNKVNSVI EKMNTQFTAV GKEFNHLEKR IENLNKKVDD GFLDIWTYNA ELLVLLENER TLDYHDSNVK NLYEKVRSQL KNNAKEIGNG CFEFYHKCDN TCMESVKNGT YDYPKYSEEA KLNREEIDGV KLESTRIYQI LAIYSTVASS LVLVVSLGAI SFWMCSNGSL QCRICIXXX
NT Sequence
atgaaggcaa tactagtagt tctgctatat acatttgcaa ccgcaaatgc agacacatta tgtataggtt atcatgcgaa caattcaaca gacactgtag acacagtact agaaaagaat gtaacagtaa cacactctgt taaccttcta gaagacaagc ataacgggaa actatgcaaa ctaagagggg tagccccatt gcatttgggt aaatgtaaca ttgctggctg gatcctggga aatccagagt gtgaatcact ctccacagca agctcatggt cctacattgt ggaaacacct agttcagaca atggaacgtg ttacccagga gatttcatcg attatgagga gctaagagag caattgagct cagtgtcatc atttgaaagg tttgagatat tccccaagac aagttcatgg cccaatcatg actcgaacaa aggtgtaacg gcagcatgtc ctcatgctgg agcaaaaagc ttctacaaaa atttaatatg gctagttaaa aaaggaaatt catacccaaa gctcagcaaa tcctacatta atgataaagg gaaagaagtc ctcgtgctat ggggcattca ccatccacct actagtgctg accaacaaag tctctatcag aatgcagatg catatgtttt tgtggggtca tcaagataca gcaagaagtt caagccggaa atagcaataa gacccaaagt gagggatcaa gaagggagaa tgaactatta ctggacacta gtagagccgg gagacaaaat aacattcgaa gcaactggaa atctagtggt accgagatat gcattcgcaa tggaaagaaa tgctggatct ggtattatca tttcagatac accagtccac gattgcaata caacttgtca aacacccaag ggtgctataa acaccagcct cccatttcag aatatacatc cgatcacaat tggaaaatgt ccaaaatatg taaaaagcac aaaattgaga ctggccacag gattgaggaa tatcccgtct attcaatcta gaggcctatt tggggccatt gccggtttca ttgaaggggg gtggacaggg atggtagatg gatggtacgg ttatcaccat caaaatgagc aggggtcagg atatgcagcc gacctgaaga gcacacagaa tgccattgac gagattacta acaaagtaaa ttctgttatt gaaaagatga atacacagtt cacagcagta ggtaaagagt tcaaccacct ggaaaaaaga atagagaatt taaataaaaa agttgatgat ggtttcctgg acatttggac ttacaatgcc gaactgttgg ttctattgga aaatgaaaga actttggact accacgattc aaatgtgaag aacttatatg aaaaggtaag aagccagcta aaaaacaatg ccaaggaaat tggaaacggc tgctttgaat tttaccacaa atgcgataac acgtgcatgg aaagtgtcaa aaatgggact tatgactacc caaaatactc agaggaagca aaattaaaca gagaagaaat agatggggta aagctggaat caacaaggat ttaccagatt ttggcgatct attcaactgt cgccagttca ttggtactgg tagtctccct gggggcaatc agtttctgga tgtgctctaa tgggtctcta cagtgtagaa tatgtattnn nnnnnnntaa