InvaG.00004.ra
RNA promoter (binds RNA-dependent RNA polymerase)
| CENTER ID: | InvaG.00004.ra |
| ORGANISM: | Influenzavirus A Influenza A virus H1N1 subtype |
| ASSOCIATED DISEASE: | Influenza |
| CURRENT STATUS: | in PDB |
| COMMUNITY REQUEST: | True |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | True |
| NIH PRIORITY pathogens category: |
IIIC |
Ordering Clones & Proteins
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Structures
2LWK
DEPOSITED: 8/1/2012
DETERMINATION: NMR
CLONE: InvaG.00004.ra.K1.GE00001
PROTEIN: InvaG.00004.ra.K1.PU00023
Publications by SSGCID
Targeting Influenza A Virus RNA Promoter
Bottini A, De SK, Pellecchia M, Varani G, Wu B, Tang C
Chem Biol Drug Des - 2015
volume 86, issue 4, pages 663-73
PMID: 25676805; PMCID: PMC4531110
PDB:
2LWK
A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication.
Bardaro MF, Bottini A, Choi BS, Kim M, Lee MK, Pellecchia M, Varani G, Zhang Z
Chem. Commun. (Camb.) - 2013
volume 50, issue 3, pages 368-70
PMID: 24247110; PMCID: PMC3894927
PDB:
2LWK
External Resources
| RESOURCE | REFERENCE ID |
|---|---|
| GenBank: | 402550035 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
X
NT Sequence
GAGTAGAAAC AAGGCTTCGG CCTGCTTTTG CT