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Seattle Structural Genomics Center for Infectious Disease

EbzaA.19907.a: Envelope glycoprotein (GP)

Target Characteristics

from organism: Ebolavirus Zaire ebolavirus Mayinga-76
most recent status: in PDB
center reference id: EbzaA.19907.a
is community request: True
associated disease: Hemorrhagic fever
NIH risk group: 4
is select agent: True
NIH priority
pathogens category:
IIIA

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Structures

image of structure for 6NAE
6NAE
Deposited: 12/5/2018
Determination: XRay
Diffraction Image
Clone: EbzaA.19907.a.HE11.GE42284
Protein: EbzaA.19907.a.HE11.PD38326
image of structure for 7LYD
7LYD
Deposited: 3/6/2021
Determination: XRay
Diffraction Image
Clone: EbzaA.19907.a.HE11.GE42284
Protein: EbzaA.19907.a.HE11.PD38351
image of structure for 7LYY
7LYY
Deposited: 3/8/2021
Determination: XRay
Diffraction Image
Clone: EbzaA.19907.a.HE11.GE42284
Protein: EbzaA.19907.a.HE11.PD38351
image of structure for 7M2D
7M2D
Deposited: 3/16/2021
Determination: XRay
Diffraction Image
Clone: EbzaA.19907.a.HE11.GE42284
Protein: EbzaA.19907.a.HE11.PD38351

Publications by SSGCID

Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors
Abendroth JA, Bullen J, Dranow DM, McCormack K, Smutney H
ACS Med Chem Lett - 2020
volume 11, issue 6, pages 1160-1167
PMID: 32550996; PMCID: PMC7294737
PDB: 6NAE

External Resources

Resource Reference ID
PATRIC ID: fig|186538.214.CDS.4
UniProt: Q05320
ViPR: link
ViPR: link
ViPR: link
ViPR: link
ViPR: link
ViPR: link
ViPR: link

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
[sequence withheld]

NT Sequence
[sequence withheld]

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