CrpaA.17789.a

Secreted pepsinogen-like aspartyl protease having a signal peptide

CENTER ID: CrpaA.17789.a
ORGANISM: Cryptosporidium parvum Iowa II
ASSOCIATED DISEASE: cryptosporidiosis - (diarrheal disease)
CURRENT STATUS: soluble
COMMUNITY REQUEST: True
NIH RISK GROUP: 2
SELECT AGENT: False
NIH PRIORITY
pathogens category:		 IIIB

Ordering Clones & Proteins

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Clones*

CENTER
REFERENCE ID		 DOMAIN/REGION
DESCRIPTION		 INFO AA
START		 AA
STOP		 ORDER
MATERIAL
CrpaA.17789.a.A3.GE46267 ordered domain 151 633
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.
NOTE: Effective as of September 1, 2026, SSGCID will no longer ship physical clone glycerols. SSGCID will provide amino acid and nucleotide sequences for any clones ordered, which the ordering party can then use to order the clone from a third-party clone manufacturer.

External Resources

RESOURCE REFERENCE ID
EuPathDB: CryptoDB:cgd6_660
UniProt: Q5CXL0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MGTISSIINY LLLLIAILNI KQTEKLTLIN SSNKIINHIN LLKNDEIFEV SGNLTNEDVY KWATSYRDYE QDSEHDHEND YDADIEDNID DDDDDYDDDD HHHHRDRIHN NKYEDHNQYQ NSLSLNKSKL IYSDSESFLI NPKLKNIYDF SNNKQIYKTI NVLNVNGEII PYDVFITNIT IPLFEVKNSL FVCRIRIGEP EQEFWPIIDT GSSNLWVIGE ECNQSSCQKV KRYSKYISKS FKRISKYDNI SVIFGTGKIY GKLILETLKF DNFQLNKHVI GIIEQVENTE NSKIDIFDAI ELEGVLGLGF TQMSSSKKLQ LPLIERLQSQ GLIQNNIFSI YINDYRIKPI NNNDKLSKPC AILLLGGIDQ NLFEEELHIL PVIREHYWQV ELESLYIGDT KYCCDYGSLA YEWENLENEH LYKKFGHYED PPMDVYIYKT FNKSIDKTNR TPGYVIFDSG TSFYTLPNFE YNHFIKEYQP FGDCSQIHLD SKKIDPKIIQ HFPNITYTFK DGFQLVIPPE LYLTPNEQGK CKPGIMMIDV PGEYGHSYLL GSLFMRSYYT VYAKNIPKIG SAVGIAKAKH NKDTRKYIYS KLSSINETFV PPDDDEAELY WTQINGRLSE NWKFPPILGN LFF
NT Sequence
atgggtacca tttcatcaat aattaattat ttattactat taatagccat tttgaatatt aaacaaacag aaaaattaac tttaataaat tcctccaata aaattattaa ccatataaac ttattgaaaa atgatgaaat ttttgaagtt tctggtaact tgaccaatga agatgtatat aaatgggcaa catcttatcg tgattatgaa caagattcag aacatgatca tgaaaatgac tatgatgctg atattgaaga taacattgat gatgatgatg atgattatga tgatgatgat catcatcatc atcgtgatcg tattcataat aacaaatatg aagatcataa ccagtaccaa aactctctta gtttaaataa atcaaaactt atatactcag actccgaatc tttcctaatt aacccaaaat taaagaatat ttatgatttt tcaaataata aacaaattta taaaaccatt aatgtattaa atgtgaatgg agaaattata ccatatgatg tttttatcac taatattacc ataccactct ttgaagtgaa aaattcactt tttgtatgta gaattagaat tggtgaacct gaacaagaat tttggcctat tattgatact ggaagcagta atctttgggt tattggagaa gaatgtaacc aatcaagttg tcaaaaagtt aaaagatatt cgaaatatat ttcaaaatca tttaaaagaa tttccaaata tgataatatt tcagtaattt ttggtactgg taaaatttat ggtaaattaa ttcttgaaac acttaaattt gataatttcc aacttaataa acatgttatt ggaattattg aacaagtgga aaatactgaa aatagcaaaa ttgatatatt tgatgcaatc gaacttgaag gtgtacttgg acttggattt acacaaatgt cttcttcaaa aaaacttcaa ctacctttaa ttgaaagact tcaaagtcaa ggacttattc aaaataatat attttctata tatattaatg attatagaat taaaccaatt aataataatg ataaactttc aaaaccttgt gctattttat tacttggtgg aattgatcaa aatctatttg aagaagaact tcatattctt ccagttatta gagaacatta ttggcaagtt gaattagaat cactttatat tggagataca aaatattgtt gtgactatgg atctcttgct tatgaatggg aaaatcttga aaatgaacat ttatataaaa aatttggaca ttacgaagat cctccaatgg atgtttatat ttacaaaact ttcaataaaa gtattgataa aactaataga actcctggat atgttatttt tgattccggt acttcttttt atacattacc caattttgaa tataatcatt ttattaaaga atatcaacct tttggtgatt gttctcaaat tcatttagat tctaaaaaga ttgatccaaa aatcattcaa cattttccta atattactta tacttttaaa gatggatttc aacttgttat tccacctgag ctttatttaa ctccaaatga acaaggaaaa tgtaaacctg gtataatgat gattgatgta ccaggtgaat atggacattc atatttactt ggttcattat ttatgagatc ttattatact gtttatgcaa aaaatatccc caagattggt tcagctgttg gtattgccaa agctaaacat aataaagata ccagaaaata tatttatagt aaactttctt cgattaatga aacatttgta cctcctgatg atgatgaagc tgaattatat tggactcaaa ttaatggaag attgtcagaa aattggaaat ttcctccaat tttaggtaat ttattctttt aa
Details for CrpaA.17789.a.A3.GE46267
HARVESTED ON: 7/17/2026
SEQUENCED ON: data unavailable
EXPECTED MW: 58kDa
OBSERVED MW: 58kDa
ANTIBIOTIC MARKER: ampicillin
COUNT OF EXPRESSION COLONIES: Good (10-50)
TOTAL EXPRESSION LEVEL: High Expression
SOLUBLE EXPRESSION LEVEL Data Unavailable
EXPRESSION HOST: BL 21 (DE3) Rosetta
SEQUENCING RESULT:
PERCENT IDENTITY: data unavailable
PERCENT COVERAGE: data unavailable
Validated AA Sequence
sequence unavailable
Validated NT Sequence
sequence unavailable
Expected Protein Sequence
MAHHHHHHMG TLEAQTQGPG SSNNKQIYKT INVLNVNGEI IPYDVFITNI TIPLFEVKNS LFVCRIRIGE PEQEFWPIID TGSSNLWVIG EECNQSSCQK VKRYSKYISK SFKRISKYDN ISVIFGTGKI YGKLILETLK FDNFQLNKHV IGIIEQVENT ENSKIDIFDA IELEGVLGLG FTQMSSSKKL QLPLIERLQS QGLIQNNIFS IYINDYRIKP INNNDKLSKP CAILLLGGID QNLFEEELHI LPVIREHYWQ VELESLYIGD TKYCCDYGSL AYEWENLENE HLYKKFGHYE DPPMDVYIYK TFNKSIDKTN RTPGYVIFDS GTSFYTLPNF EYNHFIKEYQ PFGDCSQIHL DSKKIDPKII QHFPNITYTF KDGFQLVIPP ELYLTPNEQG KCKPGIMMID VPGEYGHSYL LGSLFMRSYY TVYAKNIPKI GSAVGIAKAK HNKDTRKYIY SKLSSINETF VPPDDDEAEL YWTQINGRLS ENWKFPPILG NLFF
Full NT Sequence (Expression Vector + Insert)
ttcttgaaga cgaaagggcc tcgtgatacg cctattttta taggttaatg tcatgataat aatggtttct tagacgtcag gtggcacttt tcggggaaat gtgcgcggaa cccctatttg tttatttttc taaatacatt caaatatgta tccgctcatg agacaataac cctgataaat gcttcaataa tattgaaaaa ggaagagtat gagtattcaa catttccgtg tcgcccttat tccctttttt gcggcatttt gccttcctgt ttttgctcac ccagaaacgc tggtgaaagt aaaagatgct gaagatcagt tgggtgcacg agtgggttac atcgaactgg atctcaacag cggtaagatc cttgagagtt ttcgccccga agaacgtttt ccaatgatga gcacttttaa agttctgcta tgtggcgcgg tattatcccg tgttgacgcc gggcaagagc aactcggtcg ccgcatacac tattctcaga atgacttggt tgagtactca ccagtcacag aaaagcatct tacggatggc atgacagtaa gagaattatg cagtgctgcc ataaccatga gtgataacac tgcggccaac ttacttctga caacgatcgg aggaccgaag gagctaaccg cttttttgca caacatgggg gatcatgtaa ctcgccttga tcgttgggaa ccggagctga atgaagccat accaaacgac gagcgtgaca ccacgatgcc tgcagcaatg gcaacaacgt tgcgcaaact attaactggc gaactactta ctctagcttc ccggcaacaa ttaatagact ggatggaggc ggataaagtt gcaggaccac ttctgcgctc ggcccttccg gctggctggt ttattgctga taaatctgga gccggtgagc gtgggtctcg cggtatcatt gcagcactgg ggccagatgg taagccctcc cgtatcgtag ttatctacac gacggggagt caggcaacta tggatgaacg aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac tgtcagacca agtttactca tatatacttt agattgattt aaaacttcat ttttaattta aaaggatcta ggtgaagatc ctttttgata atctcatgac caaaatccct taacgtgagt tttcgttcca ctgagcgtca gaccccgtag aaaagatcaa aggatcttct tgagatcctt tttttctgcg cgtaatctgc tgcttgcaaa caaaaaaacc accgctacca gcggtggttt gtttgccgga tcaagagcta ccaactcttt ttccgaaggt aactggcttc agcagagcgc agataccaaa tactgtcctt ctagtgtagc cgtagttagg ccaccacttc aagaactctg tagcaccgcc tacatacctc gctctgctaa tcctgttacc agtggctgct gccagtggcg ataagtcgtg tcttaccggg ttggactcaa gacgatagtt accggataag gcgcagcggt cgggctgaac ggggggttcg tgcacacagc ccagcttgga gcgaacgacc tacaccgaac tgagatacct acagcgtgag ctatgagaaa gcgccacgct tcccgaaggg agaaaggcgg acaggtatcc ggtaagcggc agggtcggaa caggagagcg cacgagggag cttccagggg gaaacgcctg gtatctttat agtcctgtcg ggtttcgcca cctctgactt gagcgtcgat ttttgtgatg ctcgtcaggg gggcggagcc tatggaaaaa cgccagcaac gcggcctttt tacggttcct ggccttttgc tggccttttg ctcacatgtt ctttcctgcg ttatcccctg attctgtgga taaccgtatt accgcctttg agtgagctga taccgctcgc cgcagccgaa cgaccgagcg cagcgagtca gtgagcgagg aagcggaaga gcgcctgatg cggtattttc tccttacgca tctgtgcggt atttcacacc gcatatatgg tgcactctca gtacaatctg ctctgatgcc gcatagttaa gccagtatac actccgctat cgctacgtga ctgggtcatg gctgcgcccc gacacccgcc aacacccgct gacgcgccct gacgggcttg tctgctcccg gcatccgctt acagacaagc tgtgaccgtc tccgggagct gcatgtgtca gaggttttca ccgtcatcac cgaaacgcgc gaggcagctg cggtaaagct catcagcgtg gtcgtgaagc gattcacaga tgtctgcctg ttcatccgcg tccagctcgt tgagtttctc cagaagcgtt aatgtctggc ttctgataaa gcgggccatg ttaagggcgg ttttttcctg tttggtcact gatgcctccg tgtaaggggg atttctgttc atgggggtaa tgataccgat gaaacgagag aggatgctca cgatacgggt tactgatgat gaacatgccc ggttactgga acgttgtgag ggtaaacaac tggcggtatg gatgcggcgg gaccagagaa aaatcactca gggtcaatgc cagcgcttcg ttaatacaga tgtaggtgtt ccacagggta gccagcagca tcctgcgatg cagatccgga acataatggt gcagggcgct gacttccgcg tttccagact ttacgaaaca cggaaaccga agaccattca tgttgttgct caggtcgcag acgttttgca gcagcagtcg cttcacgttc gctcgcgtat cggtgattca ttctgctaac cagtaaggca accccgccag cctagccggg tcctcaacga caggagcacg atcatgcgca cccgtggcca ggacccaacg ctgcccgaga tgcgccgcgt gcggctgctg gagatggcgg acgcgatgga tatgttctgc caagggttgg tttgcgcatt cacagttctc cgcaagaatt gattggctcc aattcttgga gtggtgaatc cgttagcgag gtgccgccgg cttccattca ggtcgaggtg gcccggctcc atgcaccgcg acgcaacgcg gggaggcaga caaggtatag ggcggcgcct acaatccatg ccaacccgtt ccatgtgctc gccgaggcgg cataaatcgc cgtgacgatc agcggtccag tgatcgaagt taggctggta agagccgcga gcgatccttg aagctgtccc tgatggtcgt catctacctg cctggacagc atggcctgca acgcgggcat cccgatgccg ccggaagcga gaagaatcat aatggggaag gccatccagc ctcgcgtcgt gaacgccagc aagacgtagc ccagcgcgtc ggccgtaaca acaccattta aatggagtgg ttacaaatgg agtggttaat taacaacacc atttgtcgac gctctccctt atgcgactcc tgcattagga agcagcccag tagtaggttg aggccgttga gcaccgccgc cgcaaggaat ggtgcatgca aggagatggc gcccaacagt cccccggcca cggggcctgc caccataccc acgccgaaac aagcgctcat gagcccgaag tggcgagccc gatcttcccc atcggtgatg tcggcgatat aggcgccagc aaccgcacct gtggcgccgg tgatgccggc cacgatgcgt ccggcgtaga ggatcgagat ctcgatcccg cgaaattaat acgactcact atagggagac cacaacggtt tccctctaga aataattttg tttaacttta agaaggagat ataccatggc tcatcaccat caccatcata tgggtaccct ggaagctcag acccagggtc ctggttcgtc aaataataaa caaatttata aaaccattaa tgtattaaat gtgaatggag aaattatacc atatgatgtt tttatcacta atattaccat accactcttt gaagtgaaaa attcactttt tgtatgtaga attagaattg gtgaacctga acaagaattt tggcctatta ttgatactgg aagcagtaat ctttgggtta ttggagaaga atgtaaccaa tcaagttgtc aaaaagttaa aagatattcg aaatatattt caaaatcatt taaaagaatt tccaaatatg ataatatttc agtaattttt ggtactggta aaatttatgg taaattaatt cttgaaacac ttaaatttga taatttccaa cttaataaac atgttattgg aattattgaa caagtggaaa atactgaaaa tagcaaaatt gatatatttg atgcaatcga acttgaaggt gtacttggac ttggatttac acaaatgtct tcttcaaaaa aacttcaact acctttaatt gaaagacttc aaagtcaagg acttattcaa aataatatat tttctatata tattaatgat tatagaatta aaccaattaa taataatgat aaactttcaa aaccttgtgc tattttatta cttggtggaa ttgatcaaaa tctatttgaa gaagaacttc atattcttcc agttattaga gaacattatt ggcaagttga attagaatca ctttatattg gagatacaaa atattgttgt gactatggat ctcttgctta tgaatgggaa aatcttgaaa atgaacattt atataaaaaa tttggacatt acgaagatcc tccaatggat gtttatattt acaaaacttt caataaaagt attgataaaa ctaatagaac tcctggatat gttatttttg attccggtac ttctttttat acattaccca attttgaata taatcatttt attaaagaat atcaaccttt tggtgattgt tctcaaattc atttagattc taaaaagatt gatccaaaaa tcattcaaca ttttcctaat attacttata cttttaaaga tggatttcaa cttgttattc cacctgagct ttatttaact ccaaatgaac aaggaaaatg taaacctggt ataatgatga ttgatgtacc aggtgaatat ggacattcat atttacttgg ttcattattt atgagatctt attatactgt ttatgcaaaa aatatcccca agattggttc agctgttggt attgccaaag ctaaacataa taaagatacc agaaaatata tttatagtaa actttcttcg attaatgaaa catttgtacc tcctgatgat gatgaagctg aattatattg gactcaaatt aatggaagat tgtcagaaaa ttggaaattt cctccaattt taggtaattt attcttttaa acagcacgaa caagttctgc agccaagctt ctcgaggatc cggctgctaa caaagcccga aaggaagctg agttggctgc tgccaccgct gagcaataac tagcataacc ccttggggcc tctaaacggg tcttgagggg ttttttgctg aaaggaggaa ctatatccgg atatccacag gacgggtgtg gtcgccatga tcgcgtagtc gatagtggct ccaagtagcg aagcgagcag gactgggcgg cggccaaagc ggtcggacag tgctccgaga acgggtgcgc atagaaattg catcaacgca tatagcgcta gcagcacgcc atagtgactg gcgatgctgt cggaatggac gatatcccgc aagaggcccg gcagtaccgg cataaccaag cctatgccta cagcatccag ggtgacggtg ccgaggatga cgatgagcgc attgttagat ttcatacacg gtgcctgact gcgttagcaa tttaactgtg ataaactacc gcattaaagc ttatcgatga taagctgtca aacatgagaa