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Seattle Structural Genomics Center for Infectious Disease

BuceA.01377.a: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)

Target Characteristics

from organism: Burkholderia cenocepacia J2315
most recent status: in PDB
center reference id: BuceA.01377.a
is community request: True
associated disease:
NIH risk group: 3
is select agent: False
NIH priority
pathogens category:
IIIB

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Clones*

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BuceA.01377.a.B1.GE34990 full length 1 173 GE34990
* SSGCID clones represent un-induced expression constructs which have been verified by sequencing from vector primers. Clones may contain a tag, such as N-term 6xHis. Get sequence information using the button in the "info" column.

Proteins

CENTER
REFERENCE ID
DOMAIN/REGION
DESCRIPTION
INFO AA
START
AA
STOP
ORDER
MATERIAL
BuceA.01377.a.B1.PS01525 full length 1 173

Structures

image of structure for 4GRD
4GRD
Deposited: 8/24/2012
Determination: XRay
Diffraction Image
Clone: BuceA.01377.a.B1.GE34990
Protein: BuceA.01377.a.B1.PS01525

External Resources

Resource Reference ID
OrthoMCL: OG5_127668
PATRIC ID: fig|216591.5.peg.2936
RefSeq: YP_002231939.1
UniProt: B4EA21

Enzyme & Pathway Information

Pathway Pathway ID EC Number
inosine-5'-phosphate biosynthesis II PWY-6124 4.1.1.21
superpathway of purine nucleotides de novo biosynthesis I PWY-841 4.1.1.21
superpathway of purine nucleotides de novo biosynthesis II DENOVOPURINE2-PWY 5.4.99.18
superpathway of histidine, purine, and pyrimidine biosynthesis PRPP-PWY 5.4.99.18
inosine-5'-phosphate biosynthesis I PWY-6123 5.4.99.18
inosine-5'-phosphate biosynthesis III PWY-7234 5.4.99.18

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "more" button next to the name of that material.
AA Sequence
MSEIQTAHTH SAPLVGVLMG SSSDWDVMKH AVAILQEFGV PYEAKVVSAH RMPDEMFDYA EKARERGLRA IIAGAGGAAH LPGMLAAKTT VPVLGVPVAS KYLKGVDSLH SIVQMPKGVP VATFAIGEAG AANAALFAVS ILSGNSVDYA NRLAAFRVRQ NEAAHAMVLP PLE

NT Sequence
atgagcgaaa tccagactgc ccacacgcac agcgcgccgc tcgtcggcgt gctgatgggc tcgagttccg actgggacgt gatgaagcat gcggtcgcca tcctgcagga attcggcgtg ccgtacgaag cgaaggtcgt gtccgcgcac cggatgcccg acgagatgtt cgactatgcg gagaaggcgc gcgagcgcgg gctgcgtgcg atcatcgcgg gcgccggcgg cgccgcgcac ctgcccggca tgctggccgc gaagaccacg gtgccggtgc tcggcgtacc ggtcgcgagc aagtacctga agggtgtcga ttcgctgcac tcgatcgtgc agatgccgaa gggcgtgccc gtcgcgacgt tcgcgatcgg cgaggccggc gccgcgaacg ccgcgctgtt cgcggtgtcg atcctgtccg gcaactcggt cgactacgcg aaccggctcg ccgcgttccg cgtgcgccag aacgaagccg cgcacgcgat ggtgctgccg ccgctggaat ga

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