BewuV.18655.a

Spike glycoprotein (S)

CENTER ID: BewuV.18655.a
ORGANISM: Betacoronavirus SARS-CoV-2 C.37 Lambda variant
ASSOCIATED DISEASE:
CURRENT STATUS: in PDB
COMMUNITY REQUEST: False
NIH RISK GROUP: 2
SELECT AGENT: False
NIH PRIORITY
pathogens category:		 IIIC

Ordering Clones & Proteins

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Structures

8VYG
DEPOSITED: 2/8/2024
DETERMINATION: CryoEM
CLONE: BewuV.18655.a.UP2.GE45603
PROTEIN: BewuV.18655.a.UP2.PE00085

Publications by SSGCID

Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features
Veesler D, Greninger A, McCallum M, Bowen J, Brandenburg B, Sadoff J, Gray G, Roels S, Vandebosch A, Stieh D, Le Gars M, Vingerhoets J, Grinszgejn B, Goepfert P, de Sousa LP, Silva MST, Casapia M, Losso MH, Little SJ, Gaur A, Bekker L-G, Garrett N, Truyers C, Van Dromme I, Swann E, Marovich MA, Follmann D, Neuzil K, Corey L, Roychoudhury P, Hyrien O, Gilbert P
Nat Commun - 2024
volume 15, issue 1, pages 2175
PMID: 38467646; PMCID: PMC10928100
PDB: 8VYE, 8VYF, 8VYG

External Resources

RESOURCE REFERENCE ID

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MFVFLVLLPL VSSQCVNLTT RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHAIHV SGTNVIKRFD NPVLPFNDGV YFASTEKSNI IRGWIFGTTL DSKTQSLLIV NNATNVVIKV CEFQFCNDPF LGVYYHKNNK SWMESEFRVY SSANNCTFEY VSQPFLMDLE GKQGNFKNLR EFVFKNIDGY FKIYSKHTPI NLVRDLPQGF SALEPLVDLP IGINITRFQT LLALHNSSSG WTAGAAAYYV GYLQPRTFLL KYNENGTITD AVDCALDPLS ETKCTLKSFT VEKGIYQTSN FRVQPTESIV RFPNITNLCP FGEVFNATRF ASVYAWNRKR ISNCVADYSV LYNSASFSTF KCYGVCPTKL NDLCFTNVYA DSFVIRGDEV RQIAPGQTGK IADYNYKLPD DFTGCVIAWN SNNLDSKVGG NYNYQYRLFR KSNLKPFERD ISTEIYQAGS TPCNGVEGFN CYSPLQSYGF QPTNGVGYQP YRVVVLSFEL LHAPATVCGP KKSTNLVKNK CVNFNFNGLT GTGVLTESNK KFLPFQQFGR DIADTTDAVR DPQTLEILDI TPCSFGGVSV ITPGTNTSNQ VAVLYQGVNC TEVPVAIHAD QLTPTWRVYS TGSNVFQTRA GCLIGAEHVN NSYECDIPIG AGICASYQTQ TNSPRRARSV ASQSIIAYTM SLGAENSVAY SNNSIAIPTN FTISVTTEIL PVSMTKTSVD CTMYICGDST ECSNLLLQYG SFCTQLNRAL TGIAVEQDKN TQEVFAQVKQ IYKTPPIKDF GGFNFSQILP DPSKPSKRSP IEDLLFNKVT LADAGFIKQY GDCLGDIAAR DLICAQKFNG LNVLPPLLTD EMIAQYTSAL LAGTITSGWT FGAGPALQIP FPMQMAYRFN GIGVTQNVLY ENQKLIANQF NSAIGKIQDS LSSTPSALGK LQDVVNQNAQ ALNTLVKQLS SNFGAISSVL NDILSRLCPP EAEVQIDRLI TGRLQSLQTY VTQQLIRAAE IRASANLAAT KMSECVLGQS KRVDFCGKGY HLMSFPQSAP HGVVFLHVTY VPAQEKNFTT APAICHDGKA HFPREGVFVS NGTHWFVTQR NFYEPQIITT DNTFVSGNCD VVIGIVNNTV YDPLQPELDS FKEELDKYFK NHTSPDVDLG DISGINASVV NIQKEIDRLN EVAKNLNESL IDLQELGKYE QYIKWPWYIW LGFIAGLIAI VMVTIMLCCM TSCCSCLKGC CSCGSCCKFD EDDSEPVLKG VKLHYT
NT Sequence
ATGTTTGTGT TCCTTGTACT CCTGCCCCTT GTTAGCTCTC AGTGCGTTAA TCTCACGACC CGCACCCAGC TGCCGCCTGC CTACACTAAT TCCTTCACCC GCGGCGTGTA TTACCCCGAC AAGGTGTTCC GGAGCTCTGT TCTGCATTCC ACACAGGATC TTTTCCTCCC TTTTTTCTCT AACGTTACGT GGTTTCACGC CATCCACGTG TCGGGCACTA ACGTCATCAA GCGCTTTGAC AACCCGGTTC TTCCTTTTAA CGACGGTGTG TATTTTGCTT CCACGGAAAA GTCCAATATT ATCAGGGGGT GGATCTTTGG AACCACTTTG GATTCGAAGA CCCAGTCACT CCTGATTGTG AATAACGCGA CCAATGTGGT CATTAAGGTC TGCGAGTTCC AGTTCTGTAA CGACCCATTC CTCGGGGTGT ATTACCATAA GAATAACAAG AGCTGGATGG AGTCCGAGTT CAGGGTGTAT AGCTCGGCCA ATAACTGCAC CTTTGAATAT GTGTCTCAGC CATTTCTGAT GGATCTCGAG GGGAAGCAAG GCAACTTCAA GAACCTCAGG GAGTTCGTGT TCAAGAACAT CGACGGCTAT TTCAAAATCT ACAGTAAACA CACCCCGATC AATCTGGTGA GAGACCTGCC ACAGGGCTTT AGTGCCCTCG AGCCGCTGGT GGACCTGCCG ATCGGCATTA ACATCACGCG TTTCCAGACA CTTCTGGCTT TGCACAACAG CTCTAGTGGT TGGACCGCTG GCGCCGCAGC CTATTACGTG GGCTACCTGC AGCCTCGGAC ATTCCTTTTG AAATACAACG AGAACGGCAC TATCACCGAC GCCGTGGACT GCGCTCTGGA CCCTCTGTCC GAAACTAAAT GCACCCTTAA GTCCTTCACC GTCGAGAAGG GCATCTACCA GACTTCAAAT TTTCGGGTAC AGCCCACCGA GTCTATAGTC AGGTTCCCCA ACATCACTAA CCTATGTCCC TTCGGCGAGG TATTTAACGC AACGCGGTTT GCCAGCGTGT ATGCCTGGAA TAGAAAACGC ATCTCCAACT GTGTCGCTGA TTACAGTGTT CTGTATAATA GTGCTAGCTT CTCTACTTTT AAGTGTTACG GCGTGTGTCC TACCAAGCTG AACGATCTGT GTTTCACGAA TGTGTACGCC GATAGTTTTG TGATCCGCGG CGACGAGGTC AGACAGATCG CACCCGGCCA GACCGGCAAG ATAGCCGACT ACAACTACAA GCTCCCTGAT GACTTTACGG GATGTGTGAT CGCGTGGAAC TCTAATAACC TGGACTCTAA GGTGGGCGGA AACTACAACT ACCAGTACCG CCTGTTCAGG AAGTCTAACT TGAAGCCGTT CGAGCGCGAC ATCAGTACTG AGATTTACCA AGCGGGGTCC ACCCCTTGCA ATGGGGTCGA GGGCTTTAAT TGCTACAGCC CACTGCAGTC TTATGGATTC CAGCCTACCA ACGGCGTGGG CTACCAGCCA TACCGCGTGG TTGTACTGTC CTTCGAGCTC CTGCATGCCC CGGCCACCGT GTGCGGCCCG AAAAAGTCAA CTAATCTGGT GAAGAATAAG TGCGTGAATT TCAATTTCAA CGGTCTTACA GGCACCGGAG TGCTTACTGA AAGTAACAAA AAGTTTCTGC CCTTCCAGCA ATTCGGCCGT GATATCGCTG ACACAACCGA TGCGGTCCGC GACCCTCAGA CCCTGGAGAT CCTTGATATC ACCCCCTGCT CCTTCGGCGG TGTTTCCGTA ATCACCCCCG GAACAAATAC CAGTAACCAG GTCGCCGTTC TGTACCAGGG GGTGAACTGC ACGGAAGTGC CTGTCGCTAT CCACGCCGAT CAACTTACAC CAACCTGGAG AGTATACTCT ACCGGCTCCA ATGTCTTCCA GACCAGGGCA GGCTGCCTCA TCGGAGCTGA GCACGTCAAT AACAGTTACG AGTGCGATAT CCCAATCGGG GCCGGTATAT GCGCAAGTTA TCAGACTCAG ACCAATTCCC CAAGACGCGC CAGAAGCGTG GCTTCGCAAT CCATTATCGC CTATACCATG AGTCTGGGTG CTGAGAATTC TGTGGCGTAC TCTAATAACT CCATCGCTAT CCCGACCAAC TTTACCATCT CCGTGACAAC CGAGATCCTT CCTGTGTCAA TGACTAAGAC CTCTGTGGAC TGCACTATGT ATATCTGTGG GGACTCTACG GAATGTTCCA ACCTGTTGCT CCAATATGGC AGCTTCTGCA CCCAGCTGAA CAGAGCTCTG ACTGGCATTG CGGTGGAACA AGACAAAAAC ACCCAGGAGG TGTTTGCTCA GGTGAAGCAG ATCTACAAGA CTCCCCCGAT CAAGGACTTC GGTGGCTTCA ACTTTTCCCA GATTTTGCCC GACCCCAGCA AGCCCTCTAA GAGATCCCCT ATCGAGGACC TTCTGTTTAA CAAGGTGACC CTGGCCGATG CAGGATTCAT CAAACAGTAC GGGGACTGCC TCGGCGACAT CGCTGCACGC GACCTGATCT GCGCTCAGAA GTTCAATGGG TTGAACGTGC TACCTCCCCT CCTGACCGAC GAAATGATCG CGCAGTACAC CTCCGCGCTG CTCGCTGGTA CCATCACCAG TGGTTGGACT TTCGGAGCAG GTCCCGCGCT ACAAATACCC TTCCCTATGC AAATGGCATA CCGTTTCAAC GGCATCGGTG TGACCCAGAA CGTTCTGTAC GAAAATCAAA AACTCATCGC TAACCAATTC AATTCCGCCA TCGGCAAGAT CCAAGACTCC TTGTCGTCTA CCCCTTCTGC TCTAGGCAAG CTGCAGGACG TCGTGAATCA GAACGCTCAA GCACTCAACA CACTGGTGAA GCAACTGTCC TCTAACTTCG GCGCCATCAG CTCCGTTTTA AACGACATCC TCTCCCGGCT GTGTCCACCT GAGGCTGAGG TGCAGATCGA CCGCCTGATC ACTGGGCGCC TTCAGTCCCT CCAGACATAC GTTACCCAAC AGCTGATTCG TGCGGCCGAA ATTCGCGCTT CTGCCAACCT GGCTGCCACG AAGATGTCTG AGTGTGTGCT GGGCCAGTCC AAGAGAGTGG ATTTTTGCGG CAAAGGATAC CATCTGATGA GCTTCCCCCA GTCCGCGCCC CATGGCGTGG TTTTCCTCCA CGTGACCTAC GTGCCCGCAC AGGAGAAGAA CTTCACTACA GCCCCTGCCA TCTGCCACGA CGGGAAGGCA CATTTCCCCC GCGAAGGGGT GTTTGTGTCT AACGGCACTC ACTGGTTCGT GACTCAGCGT AATTTCTACG AGCCCCAGAT CATTACCACA GATAACACCT TTGTATCCGG AAACTGCGAC GTTGTCATCG GAATCGTTAA TAACACCGTG TATGACCCAC TGCAGCCGGA ACTGGACTCT TTCAAGGAAG AGCTGGACAA ATATTTCAAG AACCATACCT CCCCTGACGT CGACCTAGGC GACATCTCGG GAATCAACGC AAGTGTGGTC AACATCCAGA AAGAGATTGA TAGATTGAAC GAAGTGGCCA AGAACCTGAA CGAATCCCTG ATTGATCTGC AGGAACTCGG TAAGTACGAA CAGTATATAA AATGGCCGTG GTACATTTGG TTGGGATTCA TTGCCGGCCT CATCGCCATC GTCATGGTGA CAATCATGTT GTGTTGCATG ACATCCTGCT GTAGCTGCCT CAAGGGGTGC TGTTCTTGCG GCTCTTGCTG TAAGTTTGAC GAGGATGACT CCGAACCCGT GTTAAAGGGC GTGAAGCTCC ACTACACT