BewuU.18655.a

Spike glycoprotein

CENTER ID: BewuU.18655.a
ORGANISM: Betacoronavirus SARS-CoV-2 human/2022 [Omicron BN.1]
ASSOCIATED DISEASE:
CURRENT STATUS: in PDB
COMMUNITY REQUEST: False
NIH RISK GROUP: 2
SELECT AGENT: False
NIH PRIORITY
pathogens category:		 IIIC

Ordering Clones & Proteins

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Structures

8S9G
DEPOSITED: 3/28/2023
DETERMINATION: CryoEM
CLONE: BewuU.18655.a.K11.GE45347
PROTEIN: BewuU.18655.a.K11.PE00075

Publications by SSGCID

Neutralization, effector function and immune imprinting of Omicron variants
Kim M, Veesler D, Park YJ, Cameroni E, Lanzavecchia A, Corti D, Dang HV, Chu H, Pinto D, Beltramello M, Culap K, Guarino B, Case JB, Snell G, Diamond M, Piccoli L, Czudnochowski N, Silacci-Fregni C, Bassi J, Biggiogero M, Ceschi A, Ferrari P, Garzoni C, Schmid M, Subramaniam S, Saliba Christian, Dellota E, Addetia A, Sprouse K, Giannini O, Lombardo G, Franko N, Logue J, Giurdanella M, Stewart C, Purcell LA, Scheaffer SM, Muoio F, Dini M, Vincenzetti L, Acosta R, Johnson D, Leoni G, McAlister C, Rajesh A, Whitener B, Franzetti-Pellanda A, Zappi S, Bernasconi L, Schnell G, Yoshiyama C
Nature - 2023
volume 621, issue 7979, pages 592–601
PMID: 37648855; PMCID: PMC10511321
PDB: 8FXB, 8FXC, 8S9G

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MFVFLVLLPL VSSQCVNLIT RTQSYTNSFT RGVYYPDKVF RSSVLHSTQD LFLPFFSNVT WFHAIHVSGT NGTKRFDNPV LPFNDGVYFA STEKSNIIRG WIFGTTLDSK TQSLLIVNNA TNVVIKVCEF QFCNDPFLDV YYHENNKSRM ESELRVYSSA NNCTFEYVSQ PFLMDLEGKQ GNFKNLREFV FKNIDGYFKI YSKHTPVNLG RDLPQGFSAL EPLVDLPIGI NITRFQTLLA LHRSYLTPGD SSSSWTAGAA AYYVGYLQPR TFLLKYNENG TITDAVDCAL DPLSETKCTL KSFTVEKGIY QTSNFRVQPT ESIVRFPNIT NLCPFHEVFN ATTFASVYAW NRTRISNCVA DYSVLYNFAP FFAFKCYGVS PTKLNDLCFT NVYADSFVIR GNEVSQIAPG QTGNIADYNY KLPDDFTGCV IAWNSNKLDS KVSGNYNYLY RLFRKSKLKP FERDISTEIY QAGNKPCNGV AGFNCYSPLQ SYGFRPTYGV GHQPYRVVVL SFELLHAPAT VCGPKKSTNL VKNKCVNFNF NGLTGTGVLT ESNKKFLPFQ QFGRDIADTT DAVRDPQTLE ILDITPCSFG GVSVITPGTN TSNQVAVLYQ GVNCTEVPVA IHADQLTPTW RVYSTGSNVF QTRAGCLIGA EYVNNSYECD IPIGAGICAS YQTQTKSHRA AASVASQSII AYTMSLGAEN SVAYSNNSIA IPTNFTISVT TEILPVSMTK TSVDCTMYIC GDSTECSNLL LQYGSFCTQL KRALTGIAVE QDKNTQEVFA QVKQIYKTPP IKYFGGFNFS QILPDPSKPS KRSPIEDLLF NKVTLADAGF IKQYGDCLGD IAARDLICAQ KFNGLTVLPP LLTDEMIAQY TSALLAGTIT SGWTFGAGPA LQIPFPMQMA YRFNGIGVTQ NVLYENQKLI ANQFNSAIGK IQDSLSSTPS ALGKLQDVVN HNAQALNTLV KQLSSKFGAI SSVLNDILSR LDPPEAEVQI DRLITGRLQS LQTYVTQQLI RAAEIRASAN LAATKMSECV LGQSKRVDFC GKGYHLMSFP QSAPHGVVFL HVTYVPAQEK NFTTAPAICH DGKAHFPREG VFVSNGTHWF VTQRNFYEPQ IITTDNTFVS GNCDVVIGIV NNTVYDPLQP ELDSFKEELD KYFKNHTSPD VDLGDISGIN ASVVNIQKEI DRLNEVAKNL NESLIDLQEL GKYEQYIKWP WYIWLGFIAG LIAIVMVTIM LCCMTSCCSC LKGCCSCGSC CKFDEDDSEP VLKGVKLHYT
NT Sequence
ATGTTCGTCT TCCTTGTGCT TCTGCCGCTC GTGAGCTCCC AGTGTGTGAA CCTGATCACG CGTACTCAGT CGTACACCAA CTCGTTTACA CGCGGCGTCT ATTACCCTGA CAAGGTCTTC CGTTCCAGCG TGCTTCATAG CACCCAGGAC TTGTTCCTTC CATTTTTCTC CAACGTCACC TGGTTCCACG CGATCCATGT GAGTGGGACA AACGGCACTA AGCGATTTGA CAACCCTGTG CTGCCTTTTA ATGATGGCGT GTACTTTGCG AGCACCGAAA AGTCTAACAT CATTCGCGGC TGGATCTTCG GAACAACTCT GGACTCTAAG ACCCAAAGCC TCCTGATCGT TAACAATGCC ACCAACGTCG TGATCAAAGT GTGTGAGTTC CAGTTTTGCA ACGACCCATT TCTCGACGTG TATTACCACG AAAATAACAA GAGCAGGATG GAGAGCGAAT TACGTGTCTA TAGCTCGGCC AATAACTGCA CTTTCGAGTA CGTTTCCCAG CCCTTTCTGA TGGACCTGGA AGGAAAGCAA GGTAATTTCA AAAACCTGAG GGAGTTCGTC TTCAAGAACA TTGACGGCTA CTTCAAGATT TACTCCAAAC ACACCCCTGT GAACCTCGGC AGGGACCTCC CGCAGGGCTT CAGTGCACTG GAACCCCTGG TCGATCTCCC CATTGGAATC AACATCACCA GATTCCAGAC TCTGCTCGCT CTTCATCGCT CATATCTGAC GCCTGGTGAC AGCTCAAGCT CCTGGACCGC GGGAGCCGCT GCGTATTACG TGGGGTACCT GCAGCCCCGC ACCTTCTTAC TGAAATATAA CGAGAACGGC ACCATCACTG ACGCGGTCGA CTGTGCACTG GATCCCCTTT CCGAAACCAA GTGTACACTG AAGAGCTTTA CCGTCGAAAA GGGCATCTAC CAGACAAGCA ATTTCAGAGT CCAGCCCACA GAGAGCATTG TGAGGTTTCC AAACATCACT AACCTGTGCC CTTTCCACGA GGTGTTCAAC GCTACTACAT TCGCCTCCGT GTATGCCTGG AACCGCACCA GGATCTCAAA CTGTGTGGCC GACTACTCGG TGCTGTACAA CTTTGCCCCC TTCTTTGCTT TTAAATGCTA CGGAGTGTCC CCAACTAAGC TAAATGACCT GTGCTTCACC AATGTGTACG CCGACTCTTT TGTGATTCGC GGTAACGAGG TGAGCCAGAT CGCTCCAGGC CAAACCGGTA ACATCGCCGA TTATAACTAT AAATTGCCCG ATGACTTCAC CGGATGCGTA ATCGCGTGGA ACTCCAACAA GCTGGACTCT AAGGTCAGCG GCAACTACAA CTATCTGTAC CGCCTGTTTA GGAAGAGCAA GCTGAAACCC TTCGAGCGCG ATATCTCCAC TGAGATATAT CAAGCTGGCA ACAAGCCGTG TAATGGAGTG GCCGGCTTTA ATTGCTATAG CCCACTGCAG TCGTACGGCT TTCGGCCTAC TTACGGCGTT GGCCATCAGC CGTACAGAGT GGTCGTGCTG AGCTTTGAGT TGCTCCACGC ACCAGCCACT GTGTGTGGCC CCAAAAAGTC TACTAACCTG GTCAAGAACA AGTGTGTGAA CTTCAATTTC AACGGCCTGA CCGGCACCGG TGTTTTGACC GAGTCGAATA AAAAGTTTCT GCCTTTCCAA CAGTTCGGTC GCGACATCGC CGACACTACC GACGCGGTGA GAGACCCACA GACCCTGGAG ATCCTGGACA TTACTCCCTG TAGTTTCGGA GGCGTGAGCG TGATCACACC TGGCACAAAC ACCTCTAACC AGGTGGCTGT GCTGTACCAA GGTGTGAATT GCACGGAGGT GCCGGTGGCC ATTCACGCAG ACCAGCTCAC GCCAACCTGG CGTGTTTATT CTACGGGCTC CAACGTCTTC CAGACTCGGG CCGGTTGTTT GATCGGCGCT GAGTATGTGA ATAACTCCTA TGAGTGCGAT ATTCCGATCG GGGCTGGGAT TTGCGCTTCG TACCAGACAC AGACCAAGTC CCACAGGGCC GCGGCCTCTG TGGCGAGCCA AAGTATTATC GCGTACACCA TGTCCCTGGG CGCGGAGAAT TCTGTGGCTT ACTCCAATAA CTCCATTGCC ATCCCCACCA ACTTCACAAT CTCAGTCACC ACTGAGATAC TGCCAGTGAG CATGACCAAG ACATCTGTGG ACTGCACCAT GTATATCTGC GGCGACTCGA CCGAATGTTC TAATCTACTC CTGCAATACG GGTCTTTCTG TACACAGCTT AAAAGGGCTC TGACAGGCAT CGCTGTGGAG CAGGATAAGA ACACTCAGGA GGTCTTTGCT CAGGTGAAGC AGATCTACAA AACACCCCCT ATCAAATACT TTGGTGGCTT CAACTTCTCT CAGATTCTGC CAGATCCCTC CAAGCCCTCA AAGCGCTCTC CGATCGAAGA CTTGCTGTTC AATAAGGTAA CCTTGGCCGA TGCTGGGTTC ATTAAACAGT ATGGCGACTG CCTGGGCGAT ATCGCGGCCC GTGATTTGAT CTGCGCGCAG AAGTTTAACG GGCTGACCGT TCTTCCACCC CTGTTAACTG ACGAGATGAT CGCACAGTAT ACCAGCGCCC TGCTTGCCGG AACCATTACG TCCGGTTGGA CTTTTGGTGC CGGTCCTGCA CTGCAGATTC CGTTCCCAAT GCAGATGGCG TATCGGTTCA ACGGCATAGG GGTGACCCAG AACGTATTGT ACGAGAACCA GAAACTCATC GCCAACCAGT TTAATTCTGC TATCGGAAAG ATCCAGGATT CCCTGTCTTC CACCCCGTCC GCCCTTGGTA AGCTGCAGGA CGTGGTCAAC CATAACGCCC AGGCTCTGAA TACCCTGGTG AAGCAGTTGT CTTCCAAGTT TGGCGCTATT TCGTCCGTTC TGAACGACAT CCTGAGCCGA CTGGATCCTC CCGAGGCGGA GGTTCAAATC GACCGTCTGA TCACAGGCAG ACTGCAGAGT TTGCAAACAT ACGTCACCCA GCAACTCATC AGGGCTGCGG AGATCCGCGC GTCTGCCAAT TTAGCAGCGA CAAAGATGTC TGAGTGCGTG CTGGGTCAAT CCAAACGTGT AGACTTCTGC GGCAAGGGCT ATCACCTCAT GTCCTTCCCG CAAAGCGCTC CGCACGGTGT TGTCTTTCTG CACGTGACCT ACGTCCCCGC GCAGGAGAAG AATTTTACCA CAGCCCCGGC CATTTGTCAC GACGGTAAGG CTCACTTCCC CCGCGAGGGC GTTTTTGTGA GCAATGGCAC ACATTGGTTC GTCACCCAAC GCAACTTCTA CGAACCACAA ATTATCACTA CCGACAACAC TTTCGTGAGC GGCAACTGTG ATGTTGTGAT CGGTATTGTC AACAATACCG TTTATGATCC TCTGCAGCCA GAACTGGACT CCTTCAAGGA AGAGCTCGAC AAATACTTTA AGAACCACAC CTCTCCTGAC GTCGACCTGG GAGATATTAG CGGAATTAAC GCTAGCGTTG TGAACATCCA GAAGGAAATT GATAGGTTGA ACGAAGTGGC CAAGAACCTG AACGAGTCCC TGATCGACCT GCAAGAGCTG GGTAAGTATG AGCAATACAT CAAATGGCCG TGGTACATCT GGCTCGGCTT CATCGCCGGT CTCATAGCCA TAGTGATGGT GACCATTATG TTATGCTGTA TGACCAGCTG CTGTAGCTGC CTGAAAGGGT GTTGCAGTTG CGGATCTTGT TGCAAGTTTG ATGAAGATGA CTCCGAACCC GTTCTGAAGG GCGTTAAGTT GCACTACACT