BewuT.18655.a
Spike glycoprotein
| CENTER ID: | BewuT.18655.a |
| ORGANISM: | Betacoronavirus SARS-CoV-2 human/Nigeria/2022 [Omicron BQ.1.1] |
| ASSOCIATED DISEASE: | |
| CURRENT STATUS: | in PDB |
| COMMUNITY REQUEST: | False |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | False |
| NIH PRIORITY pathogens category: |
IIIC |
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Structures
8FXC
DEPOSITED: 1/24/2023
DETERMINATION: CryoEM
CLONE: BewuT.18655.a.K11.GE45346
PROTEIN: BewuT.18655.a.K11.PE00074
Publications by SSGCID
Neutralization, effector function and
immune imprinting of Omicron variants
Kim M, Veesler D, Park YJ, Cameroni E, Lanzavecchia A, Corti D, Dang HV, Chu H, Pinto D, Beltramello M, Culap K, Guarino B, Case JB, Snell G, Diamond M, Piccoli L, Czudnochowski N, Silacci-Fregni C, Bassi J, Biggiogero M, Ceschi A, Ferrari P, Garzoni C, Schmid M, Subramaniam S, Saliba Christian, Dellota E, Addetia A, Sprouse K, Giannini O, Lombardo G, Franko N, Logue J, Giurdanella M, Stewart C, Purcell LA, Scheaffer SM, Muoio F, Dini M, Vincenzetti L, Acosta R, Johnson D, Leoni G, McAlister C, Rajesh A, Whitener B, Franzetti-Pellanda A, Zappi S, Bernasconi L, Schnell G, Yoshiyama C
Nature - 2023
PMID: 37648855; PMCID: PMC10511321
External Resources
| RESOURCE | REFERENCE ID |
|---|---|
| UniProt: | A12347 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MFVFLVLLPL VSSQCVNLIT RTQSYTNSFT RGVYYPDKVF RSSVLHSTQD LFLPFFSNVT WFHAISGTNG TKRFDNPVLP FNDGVYFAST EKSNIIRGWI FGTTLDSKTQ SLLIVNNATN VVIKVCEFQF CNDPFLDVYY HKNNKSWMES EFRVYSSANN CTFEYVSQPF LMDLEGKQGN FKNLREFVFK NIDGYFKIYS KHTPINLGRD LPQGFSALEP LVDLPIGINI TRFQTLLALH RSYLTPGDSS SGWTAGAAAY YVGYLQPRTF LLKYNENGTI TDAVDCALDP LSETKCTLKS FTVEKGIYQT SNFRVQPTES IVRFPNITNL CPFDEVFNAT TFASVYAWNR KRISNCVADY SVLYNFAPFF AFKCYGVSPT KLNDLCFTNV YADSFVIRGN EVSQIAPGQT GNIADYNYKL PDDFTGCVIA WNSNKLDSTV GGNYNYRYRL FRKSKLKPFE RDISTEIYQA GNKPCNGVAG VNCYFPLQSY GFRPTYGVGH QPYRVVVLSF ELLHAPATVC GPKKSTNLVK NKCVNFNFNG LTGTGVLTES NKKFLPFQQF GRDIADTTDA VRDPQTLEIL DITPCSFGGV SVITPGTNTS NQVAVLYQGV NCTEVPVAIH ADQLTPTWRV YSTGSNVFQT RAGCLIGAEY VNNSYECDIP IGAGICASYQ TQTKSHRRAR SVASQSIIAY TMSLGAENSV AYSNNSIAIP TNFTISVTTE ILPVSMTKTS VDCTMYICGD STECSNLLLQ YGSFCTQLKR ALTGIAVEQD KNTQEVFAQV KQIYKTPPIK YFGGFNFSQI LPDPSKPSKR SFIEDLLFNK VTLADAGFIK QYGDCLGDIA ARDLICAQKF NGLTVLPPLL TDEMIAQYTS ALLAGTITSG WTFGAGAALQ IPFAMQMAYR FNGIGVTQNV LYENQKLIAN QFNSAIGKIQ DSLSSTASAL GKLQDVVNHN AQALNTLVKQ LSSKFGAISS VLNDILSRLD KVEAEVQIDR LITGRLQSLQ TYVTQQLIRA AEIRASANLA ATKMSECVLG QSKRVDFCGK GYHLMSFPQS APHGVVFLHV TYVPAQEKNF TTAPAICHDG KAHFPREGVF VSNGTHWFVT QRNFYEPQII TTDNTFVSGN CDVVIGIVNN TVYDPLQPEL DSFKEELDKY FKNHTSPDVD LGDISGINAS VVNIQKEIDR LNEVAKNLNE SLIDLQELGK YEQYIKWPWY IWLGFIAGLI AIVMVTIMLC CMTSCCSCLK GCCSCGSCCK FDEDDSEPVL KGVKLHYT
NT Sequence
ATGTTTGTTT TTCTTGTTTT ATTGCCACTA GTCTCTAGTC AGTGTGTTAA TCTTATAACC AGAACTCAAT CATACACTAA TTCTTTCACA CGTGGTGTTT ATTACCCTGA CAAAGTTTTC AGATCCTCAG TTTTACATTC AACTCAGGAC TTGTTCTTAC CTTTCTTTTC CAATGTTACT TGGTTCCATG CTATCTCTGG GACCAATGGT ACTAAGAGGT TTGATAACCC TGTCCTACCA TTTAATGATG GTGTTTATTT TGCTTCCACT GAGAAGTCTA ACATAATAAG AGGCTGGATT TTTGGTACTA CTTTAGATTC GAAGACCCAG TCCCTACTTA TTGTTAATAA CGCTACTAAT GTTGTTATTA AAGTCTGTGA ATTTCAATTT TGTAATGATC CATTTTTGGA TGTTTATTAC CACAAAAACA ACAAAAGTTG GATGGAAAGT GAGTTCAGAG TTTATTCTAG TGCGAATAAT TGCACTTTTG AATATGTCTC TCAGCCTTTT CTTATGGACC TTGAAGGAAA ACAGGGTAAT TTCAAAAATC TTAGGGAATT TGTGTTTAAG AATATTGATG GTTATTTTAA AATATATTCT AAGCACACGC CTATTAATTT AGGGCGTGAT CTCCCTCAGG GTTTTTCGGC TTTAGAACCA TTGGTAGATT TGCCAATAGG TATTAACATC ACTAGGTTTC AAACTTTACT TGCTTTACAT AGAAGTTATT TGACTCCTGG TGATTCTTCT TCAGGTTGGA CAGCTGGTGC TGCAGCTTAT TATGTGGGTT ATCTTCAACC TAGGACTTTT CTATTAAAAT ATAATGAAAA TGGAACCATT ACAGATGCTG TAGACTGTGC ACTTGACCCT CTCTCAGAAA CAAAGTGTAC GTTGAAATCC TTCACTGTAG AAAAAGGAAT CTATCAAACT TCTAACTTTA GAGTCCAACC AACAGAATCT ATTGTTAGAT TTCCTAATAT TACAAACTTG TGCCCTTTTG ATGAAGTTTT TAACGCCACC ACATTTGCAT CTGTTTATGC TTGGAACAGG AAGAGAATCA GCAACTGTGT TGCTGATTAT TCTGTCCTAT ATAATTTCGC ACCATTTTTC GCTTTTAAGT GTTATGGAGT GTCTCCTACT AAATTAAATG ATCTCTGCTT TACTAATGTC TATGCAGATT CATTTGTAAT TAGAGGTAAT GAAGTCAGCC AAATCGCTCC AGGGCAAACT GGAAATATTG CTGATTATAA TTATAAATTA CCAGATGATT TTACAGGCTG CGTTATAGCT TGGAATTCTA ACAAGCTTGA TTCTACGGTT GGTGGTAATT ATAATTACCG GTATAGATTG TTTAGGAAGT CTAAACTCAA ACCTTTTGAG AGAGATATTT CAACTGAAAT CTATCAGGCC GGTAACAAAC CTTGTAATGG TGTTGCAGGT GTTAATTGTT ACTTTCCTTT ACAATCATAT GGTTTCCGAC CCACTTATGG TGTTGGTCAC CAACCATACA GAGTAGTAGT ACTTTCTTTT GAACTTCTAC ATGCACCAGC AACTGTTTGT GGACCTAAAA AGTCTACTAA TTTGGTTAAA AACAAATGTG TCAATTTCAA CTTCAATGGT TTAACAGGCA CAGGTGTTCT TACTGAGTCT AACAAAAAGT TTCTGCCTTT CCAACAATTT GGCAGAGACA TTGCTGACAC TACTGATGCT GTCCGTGATC CACAGACACT TGAGATTCTT GACATTACAC CATGTTCTTT TGGTGGTGTC AGTGTTATAA CACCAGGAAC AAATACTTCT AACCAGGTTG CTGTTCTTTA TCAGGGTGTT AACTGCACAG AAGTCCCTGT TGCTATTCAT GCAGATCAAC TTACTCCTAC TTGGCGTGTT TATTCTACAG GTTCTAATGT TTTTCAAACA CGTGCAGGCT GTTTAATAGG GGCTGAATAT GTCAACAACT CATATGAGTG TGACATACCC ATTGGTGCAG GTATATGCGC TAGTTATCAG ACTCAGACTA AGTCTCATCG GCGGGCACGT AGTGTAGCTA GTCAATCCAT CATTGCCTAC ACTATGTCAC TTGGTGCAGA AAATTCAGTT GCTTACTCTA ATAACTCTAT TGCCATACCC ACAAATTTTA CTATTAGTGT TACCACAGAA ATTCTACCAG TGTCTATGAC CAAGACATCA GTAGATTGTA CAATGTACAT TTGTGGTGAT TCAACTGAAT GCAGCAATCT TTTGTTGCAA TATGGCAGTT TTTGTACACA ATTAAAACGT GCTTTAACTG GAATAGCTGT TGAACAAGAC AAAAACACCC AAGAAGTTTT TGCACAAGTC AAACAAATTT ACAAAACACC ACCAATTAAA TATTTTGGTG GTTTTAATTT TTCACAAATA TTACCAGATC CATCAAAACC AAGCAAGAGG TCATTTATTG AAGATCTACT TTTCAACAAA GTGACACTTG CAGATGCTGG CTTCATCAAA CAATATGGTG ATTGCCTTGG TGATATTGCT GCTAGAGACC TCATTTGTGC ACAAAAGTTT AACGGCCTTA CTGTTTTGCC ACCTTTGCTC ACAGATGAAA TGATTGCTCA ATACACTTCT GCACTGTTAG CGGGTACAAT CACTTCTGGT TGGACCTTTG GTGCAGGTGC TGCATTACAA ATACCATTTG CTATGCAAAT GGCTTATAGG TTTAATGGTA TTGGAGTTAC ACAGAATGTT CTCTATGAGA ACCAAAAATT GATTGCCAAC CAATTTAATA GTGCTATTGG CAAAATTCAA GACTCACTTT CTTCCACAGC AAGTGCACTT GGAAAACTTC AAGATGTGGT CAACCATAAT GCACAAGCTT TAAACACGCT TGTTAAACAA CTTAGCTCCA AATTTGGTGC AATTTCAAGT GTTTTAAATG ATATCCTTTC ACGTCTTGAC AAAGTTGAGG CTGAAGTGCA AATTGATAGG TTGATCACAG GCAGACTTCA AAGTTTGCAG ACATATGTGA CTCAACAATT AATTAGAGCT GCAGAAATCA GAGCTTCTGC TAATCTTGCT GCTACTAAAA TGTCAGAGTG TGTACTTGGA CAATCAAAAA GAGTTGATTT TTGTGGAAAG GGCTATCATC TTATGTCCTT CCCTCAGTCA GCACCTCATG GTGTAGTCTT CTTGCATGTG ACTTATGTCC CTGCACAAGA AAAGAACTTC ACAACTGCTC CTGCCATTTG TCATGATGGA AAAGCACACT TTCCTCGTGA AGGTGTCTTT GTTTCAAATG GCACACACTG GTTTGTAACA CAAAGGAATT TTTATGAACC ACAAATCATT ACTACAGACA ACACATTTGT GTCTGGTAAC TGTGATGTTG TAATAGGAAT TGTCAACAAC ACAGTTTATG ATCCTTTGCA ACCTGAATTA GATTCATTCA AGGAGGAGTT AGATAAATAT TTTAAGAATC ATACATCACC AGATGTTGAT TTAGGTGACA TCTCTGGCAT TAATGCTTCA GTTGTAAACA TTCAAAAAGA AATTGACCGC CTCAATGAGG TTGCCAAGAA TTTAAATGAA TCTCTCATCG ATCTCCAAGA ACTTGGAAAG TATGAGCAGT ATATAAAATG GCCATGGTAC ATTTGGCTAG GTTTTATAGC TGGCTTGATT GCCATAGTAA TGGTGACAAT TATGCTTTGC TGTATGACCA GTTGCTGTAG TTGTCTCAAG GGCTGTTGTT CTTGTGGATC CTGCTGCAAA TTTGATGAAG ACGACTCTGA GCCAGTGCTC AAAGGAGTCA AATTACATTA CACA