BewuL.18655.a

Spike glycoprotein

CENTER ID: BewuL.18655.a
ORGANISM: Betacoronavirus SARS-CoV-2 human/USA/IN-CDC-STM-000049216/2021 []Delta B.1.617.2
ASSOCIATED DISEASE:
CURRENT STATUS: in PDB
COMMUNITY REQUEST: False
NIH RISK GROUP: 2
SELECT AGENT: False
NIH PRIORITY
pathogens category:
IIIC

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Structures
7SO9
DEPOSITED: 10/29/2021
DETERMINATION: CryoEM
CLONE: BewuL.18655.a.UP21.GE44693
PROTEIN: BewuL.18655.a.UP21.PE00045
7SOA
DEPOSITED: 10/29/2021
DETERMINATION: CryoEM
CLONE: BewuL.18655.a.UP21.GE44693
PROTEIN: BewuL.18655.a.UP21.PE00046
Publications by SSGCID
Molecular basis of immune evasion by the delta and kappa SARS-CoV-2 variants
Van Voorhis W, Walls AC, Veesler D, Corti D, Carter L, Dang HV, Chu H, De Marco A, Snell G, McCallum M, Bowen J, Miranda M, Rosen L, Pizzuto M, Tilles SW, Sprouse K, Ahlrichs M, Franko N, Logue J
Science - 2021
volume 374, issue 6575, pages 1621-1626
PMID: 34751595
PDB: 7SO9, 7SOA, 7SOB, 7SOC, 7SOD, 7SOE, 7SOF
External Resources
RESOURCE REFERENCE ID
GenBank: QUD52764
PATRIC ID: fig|2697049.1847159.peg.3
ViPR: link
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MFVFLVLLPL VSSQCVNLRT RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHAIHV SGTNGTTRFD NPVLPFNDGV YFASTEKSNI IRGWIFGTTL DSKTQSLLIV NNATNVVIKV CEFQFCNDPF LGVYYHKNNK SWMESGVYSS ANNCTFEYVS QPFLMDLEGK QGNFKNLREF VFKNIDGYFK IYSKHTPINL VRDLPQGFSA LEPLVDLPIG INITRFQTLL ALHRSYLTPG DSSSGWTAGA AAYYVGYLQP RTFLLKYNEN GTITDAVDCA LDPLSETKCT LKSFTVEKGI YQTSNFRVQP TESIVRFPNI TNLCPFGEVF NATRFASVYA WNRKRISNCV ADYSVLYNSA SFSTFKCYGV SPTKLNDLCF TNVYADSFVI RGDEVRQIAP GQTGKIADYN YKLPDDFTGC VIAWNSNNLD SKVGGNYNYR YRLFRKSNLK PFERDISTEI YQAGSKPCNG VEGFNCYFPL QSYGFQPTNG VGYQPYRVVV LSFELLHAPA TVCGPKKSTN LVKNKCVNFN FNGLTGTGVL TESNKKFLPF QQFGRDIADT TDAVRDPQTL EILDITPCSF GGVSVITPGT NTSNQVAVLY QGVNCTEVPV AIHADQLTPT WRVYSTGSNV FQTRAGCLIG AEHVNNSYEC DIPIGAGICA SYQTQTNSRR RARSVASQSI IAYTMSLGAE NSVAYSNNSI AIPTNFTISV TTEILPVSMT KTSVDCTMYI CGDSTECSNL LLQYGSFCTQ LNRALTGIAV EQDKNTQEVF AQVKQIYKTP PIKDFGGFNF SQILPDPSKP SKRSFIEDLL FNKVTLADAG FIKQYGDCLG DIAARDLICA QKFNGLTVLP PLLTDEMIAQ YTSALLAGTI TSGWTFGAGA ALQIPFAMQM AYRFNGIGVT QNVLYENQKL IANQFNSAIG KIQDSLSSTA SALGKLQNVV NQNAQALNTL VKQLSSNFGA ISSVLNDILS RLDKVEAEVQ IDRLITGRLQ SLQTYVTQQL IRAAEIRASA NLAATKMSEC VLGQSKRVDF CGKGYHLMSF PQSAPHGVVF LHVTYVPAQE KNFTTAPAIC HDGKAHFPRE GVFVSNGTHW FVTQRNFYEP QIITTDNTFV SGNCDVVIGI VNNTVYDPLQ PELDSFKEEL DKYFKNHTSP DVDLGDISGI NASVVNIQKE IDRLNEVAKN LNESLIDLQE LGKYEQYIKW PWYIWLGFIA GLIAIVMVTI MLCCMTSCCS CLKGCCSCGS CCKFDEDDSE PVLKGVKLHY T
NT Sequence
ATGTTTGTTT TTCTTGTTTT ATTGCCACTA GTCTCTAGTC AGTGTGTTAA TCTTAGAACC AGAACTCAAT TACCCCCTGC ATACACTAAT TCTTTCACAC GTGGTGTTTA TTACCCTGAC AAAGTTTTCA GATCCTCAGT TTTACATTCA ACTCAGGACT TGTTCTTACC TTTCTTTTCC AATGTTACTT GGTTCCATGC TATACATGTC TCTGGGACCA ATGGTACTAC GAGGTTTGAT AACCCTGTCC TACCATTTAA TGATGGTGTT TATTTTGCTT CCACTGAGAA GTCTAACATA ATAAGAGGCT GGATTTTTGG TACTACTTTA GATTCGAAGA CCCAGTCCCT ACTTATTGTT AATAACGCTA CTAATGTTGT TATTAAAGTC TGTGAATTTC AATTTTGTAA TGATCCATTT TTGGGTGTTT ATTACCACAA AAACAACAAA AGTTGGATGG AAAGTGGAGT TTATTCTAGT GCGAATAATT GCACTTTTGA ATATGTCTCT CAGCCTTTTC TTATGGACCT TGAAGGAAAA CAGGGTAATT TCAAAAATCT TAGGGAATTT GTGTTTAAGA ATATTGATGG TTATTTTAAA ATATATTCTA AGCACACGCC TATTAATTTA GTGCGTGATC TCCCTCAGGG TTTTTCGGCT TTAGAACCAT TGGTAGATTT GCCAATAGGT ATTAACATCA CTAGGTTTCA AACTTTACTT GCTTTACATA GAAGTTATTT GACTCCTGGT GATTCTTCTT CAGGTTGGAC AGCTGGTGCT GCAGCTTATT ATGTGGGTTA TCTTCAACCT AGGACTTTTC TATTAAAATA TAATGAAAAT GGAACCATTA CAGATGCTGT AGACTGTGCA CTTGACCCTC TCTCAGAAAC AAAGTGTACG TTGAAATCCT TCACTGTAGA AAAAGGAATC TATCAAACTT CTAACTTTAG AGTCCAACCA ACAGAATCTA TTGTTAGATT TCCTAATATT ACAAACTTGT GCCCTTTTGG TGAAGTTTTT AACGCCACCA GATTTGCATC TGTTTATGCT TGGAACAGGA AGAGAATCAG CAACTGTGTT GCTGATTATT CTGTCCTATA TAATTCCGCA TCATTTTCCA CTTTTAAGTG TTATGGAGTG TCTCCTACTA AATTAAATGA TCTCTGCTTT ACTAATGTCT ATGCAGATTC ATTTGTAATT AGAGGTGATG AAGTCAGACA AATCGCTCCA GGGCAAACTG GAAAGATTGC TGATTATAAT TATAAATTAC CAGATGATTT TACAGGCTGC GTTATAGCTT GGAATTCTAA CAATCTTGAT TCTAAGGTTG GTGGTAATTA TAATTACCGG TATAGATTGT TTAGGAAGTC TAATCTCAAA CCTTTTGAGA GAGATATTTC AACTGAAATC TATCAGGCCG GTAGCAAACC TTGTAATGGT GTTGAAGGTT TTAATTGTTA CTTTCCTTTA CAATCATATG GTTTCCAACC CACTAATGGT GTTGGTTACC AACCATACAG AGTAGTAGTA CTTTCTTTTG AACTTCTACA TGCACCAGCA ACTGTTTGTG GACCTAAAAA GTCTACTAAT TTGGTTAAAA ACAAATGTGT CAATTTCAAC TTCAATGGTT TAACAGGCAC AGGTGTTCTT ACTGAGTCTA ACAAAAAGTT TCTGCCTTTC CAACAATTTG GCAGAGACAT TGCTGACACT ACTGATGCTG TCCGTGATCC ACAGACACTT GAGATTCTTG ACATTACACC ATGTTCTTTT GGTGGTGTCA GTGTTATAAC ACCAGGAACA AATACTTCTA ACCAGGTTGC TGTTCTTTAT CAGGGTGTTA ACTGCACAGA AGTCCCTGTT GCTATTCATG CAGATCAACT TACTCCTACT TGGCGTGTTT ATTCTACAGG TTCTAATGTT TTTCAAACAC GTGCAGGCTG TTTAATAGGG GCTGAACATG TCAACAACTC ATATGAGTGT GACATACCCA TTGGTGCAGG TATATGCGCT AGTTATCAGA CTCAGACTAA TTCTCGTCGG CGGGCACGTA GTGTAGCTAG TCAATCCATC ATTGCCTACA CTATGTCACT TGGTGCAGAA AATTCAGTTG CTTACTCTAA TAACTCTATT GCCATACCCA CAAATTTTAC TATTAGTGTT ACCACAGAAA TTCTACCAGT GTCTATGACC AAGACATCAG TAGATTGTAC AATGTACATT TGTGGTGATT CAACTGAATG CAGCAATCTT TTGTTGCAAT ATGGCAGTTT TTGTACACAA TTAAACCGTG CTTTAACTGG AATAGCTGTT GAACAAGACA AAAACACCCA AGAAGTTTTT GCACAAGTCA AACAAATTTA CAAAACACCA CCAATTAAAG ATTTTGGTGG TTTTAATTTT TCACAAATAT TACCAGATCC ATCAAAACCA AGCAAGAGGT CATTTATTGA AGATCTACTT TTCAACAAAG TGACACTTGC AGATGCTGGC TTCATCAAAC AATATGGTGA TTGCCTTGGT GATATTGCTG CTAGAGACCT CATTTGTGCA CAAAAGTTTA ACGGCCTTAC TGTTTTGCCA CCTTTGCTCA CAGATGAAAT GATTGCTCAA TACACTTCTG CACTGTTAGC GGGTACAATC ACTTCTGGTT GGACCTTTGG TGCAGGTGCT GCATTACAAA TACCATTTGC TATGCAAATG GCTTATAGGT TTAATGGTAT TGGAGTTACA CAGAATGTTC TCTATGAGAA CCAAAAATTG ATTGCCAACC AATTTAATAG TGCTATTGGC AAAATTCAAG ACTCACTTTC TTCCACAGCA AGTGCACTTG GAAAACTTCA AAATGTGGTC AACCAAAATG CACAAGCTTT AAACACGCTT GTTAAACAAC TTAGCTCCAA TTTTGGTGCA ATTTCAAGTG TTTTAAATGA TATCCTTTCA CGTCTTGACA AAGTTGAGGC TGAAGTGCAA ATTGATAGGT TGATCACAGG CAGACTTCAA AGTTTGCAGA CATATGTGAC TCAACAATTA ATTAGAGCTG CAGAAATCAG AGCTTCTGCT AATCTTGCTG CTACTAAAAT GTCAGAGTGT GTACTTGGAC AATCAAAAAG AGTTGATTTT TGTGGAAAGG GCTATCATCT TATGTCCTTC CCTCAGTCAG CACCTCATGG TGTAGTCTTC TTGCATGTGA CTTATGTCCC TGCACAAGAA AAGAACTTCA CAACTGCTCC TGCCATTTGT CATGATGGAA AAGCACACTT TCCTCGTGAA GGTGTCTTTG TTTCAAATGG CACACACTGG TTTGTAACAC AAAGGAATTT TTATGAACCA CAAATCATTA CTACAGACAA CACATTTGTG TCTGGTAACT GTGATGTTGT AATAGGAATT GTCAACAACA CAGTTTATGA TCCTTTGCAA CCTGAATTAG ACTCATTCAA GGAGGAGTTA GATAAATATT TTAAGAATCA TACATCACCA GATGTTGATT TAGGTGACAT CTCTGGCATT AATGCTTCAG TTGTAAACAT TCAAAAAGAA ATTGACCGCC TCAATGAGGT TGCCAAGAAT TTAAATGAAT CTCTCATCGA TCTCCAAGAA CTTGGAAAGT ATGAGCAGTA TATAAAATGG CCATGGTACA TTTGGCTAGG TTTTATAGCT GGCTTGATTG CCATAGTAAT GGTGACAATT ATGCTTTGCT GTATGACCAG TTGCTGTAGT TGTCTCAAGG GCTGTTGTTC TTGTGGATCC TGCTGCAAAT TTGATGAAGA CGACTCTGAG CCAGTGCTCA AAGGAGTCAA ATTACATTAC ACA