BewuH.18655.a
Spike glycoprotein
| CENTER ID: | BewuH.18655.a |
| ORGANISM: | Betacoronavirus SARS-CoV-2 human/USA/FL-CDC-STM-77CPCCUR3/2022 [Omicron BA.2] |
| ASSOCIATED DISEASE: | |
| CURRENT STATUS: | in PDB |
| COMMUNITY REQUEST: | False |
| NIH RISK GROUP: | 2 |
| SELECT AGENT: | False |
| NIH PRIORITY pathogens category: |
IIIC |
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Structures
9ASD
DEPOSITED: 2/25/2024
DETERMINATION: CryoEM
CLONE: BewuH.18655.a.UP21.GE45864
PROTEIN: BewuH.18655.a.UP21.PE00092
9AU2
DEPOSITED: 2/28/2024
DETERMINATION: CryoEM
CLONE: BewuH.18655.a.UP21.GE45864
PROTEIN: BewuH.18655.a.UP21.PE00092
Publications by SSGCID
A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification
Veesler D, Park YJ, Cameroni E, Lanzavecchia A, Corti D, Dang HV, Tortorici MA, Pinto D, Zatta F, De Marco A, Guarino B, Snell G, Telenti A, Starr T, Czudnochowski N, Rosen L, Lempp F, Benigni F, Liu Z, Zepeda S, di Iulio J, Subramaniam S, Saliba Christian, Dellota E, Addetia A, Whelan SPJ, Sprouse K, Zhang I, Noack J, Giurdanella M, Hauser K, Purcell LA, Acosta R, Rajesh A, Schnell G, de Melo GD, Kergoat L, Bourhy H, Lee J, Taylor AL, Brown J, Foreman WB, Bohan D, Errico JM, Chartron JW, Cusumano G, Tao Q, Schmid MA, Pizzuto MJ
Cell - 2024
volume 187, issue 25, pages 7196-7213
PMID: 39383863; PMCID: PMC11645210
External Resources
| RESOURCE | REFERENCE ID |
|---|---|
| BV-BRC: | fig|2697049.6723457.CDS.3 |
| GenBank: | UJP23605 |
Sequences
These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols.
To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MFVFLVLLPL VSSQCVNLIT RTQSYTNSFT RGVYYPDKVF RSSVLHSTQD LFLPFFSNVT WFHAIHVSGT NGTKRFDNPV LPFNDGVYFA STEKSNIIRG WIFGTTLDSK TQSLLIVNNA TNVVIKVCEF QFCNDPFLDV YYHKNNKSWM ESEFRVYSSA NNCTFEYVSQ PFLMDLEGKQ GNFKNLREFV FKNIDGYFKI YSKHTPINLG RDLPQGFSAL EPLVDLPIGI NITRFQTLLA LHRSYLTPGD SSSGWTAGAA AYYVGYLQPR TFLLKYNENG TITDAVDCAL DPLSETKCTL KSFTVEKGIY QTSNFRVQPT ESIVRFPNIT NLCPFDEVFN ATRFASVYAW NRKRISNCVA DYSVLYNFAP FFAFKCYGVS PTKLNDLCFT NVYADSFVIR GNEVSQIAPG QTGNIADYNY KLPDDFTGCV IAWNSNKLDS KVGGNYNYLY RLFRKSNLKP FERDISTEIY QAGNKPCNGV AGFNCYFPLR SYGFRPTYGV GHQPYRVVVL SFELLHAPAT VCGPKKSTNL VKNKCVNFNF NGLTGTGVLT ESNKKFLPFQ QFGRDIADTT DAVRDPQTLE ILDITPCSFG GVSVITPGTN TSNQVAVLYQ GVNCTEVPVA IHADQLTPTW RVYSTGSNVF QTRAGCLIGA EYVNNSYECD IPIGAGICAS YQTQTKSHRR ARSVASQSII AYTMSLGAEN SVAYSNNSIA IPTNFTISVT TEILPVSMTK TSVDCTMYIC GDSTECSNLL LQYGSFCTQL KRALTGIAVE QDKNTQEVFA QVKQIYKTPP IKYFGGFNFS QILPDPSKPS KRSFIEDLLF NKVTLADAGF IKQYGDCLGD IAARDLICAQ KFNGLTVLPP LLTDEMIAQY TSALLAGTIT SGWTFGAGAA LQIPFAMQMA YRFNGIGVTQ NVLYENQKLI ANQFNSAIGK IQDSLSSTAS ALGKLQDVVN HNAQALNTLV KQLSSKFGAI SSVLNDILSR LDKVEAEVQI DRLITGRLQS LQTYVTQQLI RAAEIRASAN LAATKMSECV LGQSKRVDFC GKGYHLMSFP QSAPHGVVFL HVTYVPAQEK NFTTAPAICH DGKAHFPREG VFVSNGTHWF VTQRNFYEPQ IITTDNTFVS GNCDVVIGIV NNTVYDPLQP ELDSFKEELD KYFKNHTSPD VDLGDISGIN ASVVNIQKEI DRLNEVAKNL NESLIDLQEL GKYEQYIKWP WYIWLGFIAG LIAIVMVTIM LCCMTSCCSC LKGCCSCGSC CKFDEDDSEP VLKGVKLHYT
NT Sequence
ATGTTTGTTT TTCTTGTTTT ATTGCCACTA GTCTCTAGTC AGTGTGTTAA TCTTATAACC AGAACTCAAT CATACACTAA TTCTTTCACA CGTGGTGTTT ATTACCCTGA CAAAGTTTTC AGATCCTCAG TTTTACATTC AACTCAGGAC TTGTTCTTAC CTTTCTTTTC CAATGTTACT TGGTTCCATG CTATACATGT CTCTGGGACC AATGGTACTA AGAGGTTTGA TAACCCTGTC CTACCATTTA ATGATGGTGT TTATTTTGCT TCCACTGAGA AGTCTAACAT AATAAGAGGC TGGATTTTTG GTACTACTTT AGATTCGAAG ACCCAGTCCC TACTTATTGT TAATAACGCT ACTAATGTTG TTATTAAAGT CTGTGAATTT CAATTTTGTA ATGATCCATT TTTGGATGTT TATTACCACA AAAACAACAA AAGTTGGATG GAAAGTGAGT TCAGAGTTTA TTCTAGTGCG AATAATTGCA CTTTTGAATA TGTCTCTCAG CCTTTTCTTA TGGACCTTGA AGGAAAACAG GGTAATTTCA AAAATCTTAG GGAATTTGTG TTTAAGAATA TTGATGGTTA TTTTAAAATA TATTCTAAGC ACACGCCTAT TAATTTAGGG CGTGATCTCC CTCAGGGTTT TTCGGCTTTA GAACCATTGG TAGATTTGCC AATAGGTATT AACATCACTA GGTTTCAAAC TTTACTTGCT TTACATAGAA GTTATTTGAC TCCTGGTGAT TCTTCTTCAG GTTGGACAGC TGGTGCTGCA GCTTATTATG TGGGTTATCT TCAACCTAGG ACTTTTCTAT TAAAATATAA TGAAAATGGA ACCATTACAG ATGCTGTAGA CTGTGCACTT GACCCTCTCT CAGAAACAAA GTGTACGTTG AAATCCTTCA CTGTAGAAAA AGGAATCTAT CAAACTTCTA ACTTTAGAGT CCAACCAACA GAATCTATTG TTAGATTTCC TAATATTACA AACTTGTGCC CTTTTGATGA AGTTTTTAAC GCCACCAGAT TTGCATCTGT TTATGCTTGG AACAGGAAGA GAATCAGCAA CTGTGTTGCT GATTATTCTG TCCTATATAA TTTCGCACCA TTTTTCGCTT TTAAGTGTTA TGGAGTGTCT CCTACTAAAT TAAATGATCT CTGCTTTACT AATGTCTATG CAGATTCATT TGTAATTAGA GGTAATGAAG TCAGCCAAAT CGCTCCAGGG CAAACTGGAA ATATTGCTGA TTATAATTAT AAATTACCAG ATGATTTTAC AGGCTGCGTT ATAGCTTGGA ATTCTAACAA GCTTGATTCT AAGGTTGGTG GTAATTATAA TTACCTGTAT AGATTGTTTA GGAAGTCTAA TCTCAAACCT TTTGAGAGAG ATATTTCAAC TGAAATCTAT CAGGCCGGTA ACAAACCTTG TAATGGTGTT GCAGGTTTTA ATTGTTACTT TCCTTTACGA TCATATGGTT TCCGACCCAC TTATGGTGTT GGTCACCAAC CATACAGAGT AGTAGTACTT TCTTTTGAAC TTCTACATGC ACCAGCAACT GTTTGTGGAC CTAAAAAGTC TACTAATTTG GTTAAAAACA AATGTGTCAA TTTCAACTTC AATGGTTTAA CAGGCACAGG TGTTCTTACT GAGTCTAACA AAAAGTTTCT GCCTTTCCAA CAATTTGGCA GAGACATTGC TGACACTACT GATGCTGTCC GTGATCCACA GACACTTGAG ATTCTTGACA TTACACCATG TTCTTTTGGT GGTGTCAGTG TTATAACACC AGGAACAAAT ACTTCTAACC AGGTTGCTGT TCTTTATCAG GGTGTTAACT GCACAGAAGT CCCTGTTGCT ATTCATGCAG ATCAACTTAC TCCTACTTGG CGTGTTTATT CTACAGGTTC TAATGTTTTT CAAACACGTG CAGGCTGTTT AATAGGGGCT GAATATGTCA ACAACTCATA TGAGTGTGAC ATACCCATTG GTGCAGGTAT ATGCGCTAGT TATCAGACTC AGACTAAGTC TCATCGGCGG GCACGTAGTG TAGCTAGTCA ATCCATCATT GCCTACACTA TGTCACTTGG TGCAGAAAAT TCAGTTGCTT ACTCTAATAA CTCTATTGCC ATACCCACAA ATTTTACTAT TAGTGTTACC ACAGAAATTC TACCAGTGTC TATGACCAAG ACATCAGTAG ATTGTACAAT GTACATTTGT GGTGATTCAA CTGAATGCAG CAATCTTTTG TTGCAATATG GCAGTTTTTG TACACAATTA AAACGTGCTT TAACTGGAAT AGCTGTTGAA CAAGACAAAA ACACCCAAGA AGTTTTTGCA CAAGTCAAAC AAATTTACAA AACACCACCA ATTAAATATT TTGGTGGTTT TAATTTTTCA CAAATATTAC CAGATCCATC AAAACCAAGC AAGAGGTCAT TTATTGAAGA TCTACTTTTC AACAAAGTGA CACTTGCAGA TGCTGGCTTC ATCAAACAAT ATGGTGATTG CCTTGGTGAT ATTGCTGCTA GAGACCTCAT TTGTGCACAA AAGTTTAACG GCCTTACTGT TTTGCCACCT TTGCTCACAG ATGAAATGAT TGCTCAATAC ACTTCTGCAC TGTTAGCGGG TACAATCACT TCTGGTTGGA CCTTTGGTGC AGGTGCTGCA TTACAAATAC CATTTGCTAT GCAAATGGCT TATAGGTTTA ATGGTATTGG AGTTACACAG AATGTTCTCT ATGAGAACCA AAAATTGATT GCCAACCAAT TTAATAGTGC TATTGGCAAA ATTCAAGACT CACTTTCTTC CACAGCAAGT GCACTTGGAA AACTTCAAGA TGTGGTCAAC CATAATGCAC AAGCTTTAAA CACGCTTGTT AAACAACTTA GCTCCAAATT TGGTGCAATT TCAAGTGTTT TAAATGATAT CCTTTCACGT CTTGACAAAG TTGAGGCTGA AGTGCAAATT GATAGGTTGA TCACAGGCAG ACTTCAAAGT TTGCAGACAT ATGTGACTCA ACAATTAATT AGAGCTGCAG AAATCAGAGC TTCTGCTAAT CTTGCTGCTA CTAAAATGTC AGAGTGTGTA CTTGGACAAT CAAAAAGAGT TGATTTTTGT GGAAAGGGCT ATCATCTTAT GTCCTTCCCT CAGTCAGCAC CTCATGGTGT AGTCTTCTTG CATGTGACTT ATGTCCCTGC ACAAGAAAAG AACTTCACAA CTGCTCCTGC CATTTGTCAT GATGGAAAAG CACACTTTCC TCGTGAAGGT GTCTTTGTTT CAAATGGCAC ACACTGGTTT GTAACACAAA GGAATTTTTA TGAACCACAA ATCATTACTA CAGACAACAC ATTTGTGTCT GGTAACTGTG ATGTTGTAAT AGGAATTGTC AACAACACAG TTTATGATCC TTTGCAACCT GAATTAGATT CATTCAAGGA GGAGTTAGAT AAATATTTTA AGAATCATAC ATCACCAGAT GTTGATTTAG GTGACATCTC TGGCATTAAT GCTTCAGTTG TAAACATTCA AAAAGAAATT GACCGCCTCA ATGAGGTTGC CAAGAATTTA AATGAATCTC TCATCGATCT CCAAGAACTT GGAAAGTATG AGCAGTATAT AAAATGGCCA TGGTACATTT GGCTAGGTTT TATAGCTGGC TTGATTGCCA TAGTAATGGT GACAATTATG CTTTGCTGTA TGACCAGTTG CTGTAGTTGT CTCAAGGGCT GTTGTTCTTG TGGATCCTGC TGCAAATTTG ATGAAGACGA CTCTGAGCCA GTGCTCAAAG GAGTCAAATT ACATTACACA