BewuG.18655.a

Spike glycoprotein

CENTER ID: BewuG.18655.a
ORGANISM: Betacoronavirus SARS-CoV-2 hCoV-19/South Africa/CERI-KRISP-K032283/2021 [Omicron BA.1]
ASSOCIATED DISEASE:
CURRENT STATUS: in PDB
COMMUNITY REQUEST: False
NIH RISK GROUP: 2
SELECT AGENT: False
NIH PRIORITY
pathogens category:
IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Structures

7TLY
DEPOSITED: 1/19/2022
DETERMINATION: CryoEM
CLONE: BewuG.18655.a.UP21.GE44706
PROTEIN: BewuG.18655.a.UP21.PE00051
7TLZ
DEPOSITED: 1/19/2022
DETERMINATION: CryoEM
CLONE: BewuG.18655.a.UP21.GE44706
PROTEIN: BewuG.18655.a.UP21.PE00051
7TM0
DEPOSITED: 1/19/2022
DETERMINATION: CryoEM
CLONE: BewuG.18655.a.UP21.GE44706
PROTEIN: BewuG.18655.a.UP21.PE00054
7TN0
DEPOSITED: 1/20/2022
DETERMINATION: XRay
CLONE: BewuG.18655.a.UP21.GE44706
PROTEIN: BewuG.18655.a.UP21.PE00055
8ERQ
DEPOSITED: 10/12/2022
DETERMINATION: CryoEM
CLONE: BewuG.18655.a.UP22.GE44908
PROTEIN: BewuG.18655.a.UP22.PE00069
8ERR
DEPOSITED: 10/12/2022
DETERMINATION: CryoEM
CLONE: BewuG.18655.a.UP22.GE44908
PROTEIN: BewuG.18655.a.UP22.PE00069

Publications by SSGCID

Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement
Veesler D, Corti D, Snell G, Virgin HW, McCallum M, Bowen J, Czudnochowski N, Rosen L, Nix J, Dillen J, Zepeda S, Croll TI, Powell AE
Science - 2022
volume 375, issue 6583, pages 864-868
PMID: 35076256; PMCID: PMC9427005
PDB: 7TLY, 7TLZ, 7TM0, 7TN0
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages
Walls AC, Veesler D, Park YJ, Lanzavecchia A, Corti D, Dang HV, Chu H, Pinto D, Zatta F, De Marco A, Guarino B, Snell G, Virgin HW, Bowen J, Piccoli L, Silacci-Fregni C, Bassi J, Pizzuto M, Ceschi A, Ferrari P, Lempp F, Zhou J, Kaiser H, Benigni F, Abdelnabi R, Schmid M, Neyts J, Liu Z, di Iulio J, Saliba Christian, Addetia A, Whelan SPJ, Sprouse K, Noack J, Giannini O, Montiel_Ruiz M, Franko N, Logue J, Giurdanella M, Farhat N, Soriaga L, Hauser K, Stewart C, Purcell LA, Rajesh A, Schnell G, Rivera W, Janer J, Maes P, de Melo GD, Kergoat L, Bourhy H
Science - 2022
volume 378, issue 6620, pages 619-627
PMID: 35677069; PMCID: PMC9176643
PDB: 8ERQ, 8ERR

External Resources

RESOURCE REFERENCE ID
PATRIC ID: fig|2697049.6653242.CDS.4
UniProt: EPI_ISL_6795202_S

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MFVFLVLLPL VSSQCVNLTT RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHVISG TNGTKRFDNP VLPFNDGVYF ASIEKSNIIR GWIFGTTLDS KTQSLLIVNN ATNVVIKVCE FQFCNDPFLD HKNNKSWMES EFRVYSSANN CTFEYVSQPF LMDLEGKQGN FKNLREFVFK NIDGYFKIYS KHTPIIVREP EDLPQGFSAL EPLVDLPIGI NITRFQTLLA LHRSYLTPGD SSSGWTAGAA AYYVGYLQPR TFLLKYNENG TITDAVDCAL DPLSETKCTL KSFTVEKGIY QTSNFRVQPT ESIVRFPNIT NLCPFDEVFN ATRFASVYAW NRKRISNCVA DYSVLYNLAP FFTFKCYGVS PTKLNDLCFT NVYADSFVIR GDEVRQIAPG QTGNIADYNY KLPDDFTGCV IAWNSNKLDS KVSGNYNYLY RLFRKSNLKP FERDISTEIY QAGNKPCNGV AGFNCYFPLR SYSFRPTYGV GHQPYRVVVL SFELLHAPAT VCGPKKSTNL VKNKCVNFNF NGLKGTGVLT ESNKKFLPFQ QFGRDIADTT DAVRDPQTLE ILDITPCSFG GVSVITPGTN TSNQVAVLYQ GVNCTEVPVA IHADQLTPTW RVYSTGSNVF QTRAGCLIGA EYVNNSYECD IPIGAGICAS YQTQTKSHRR ARSVASQSII AYTMSLGAEN SVAYSNNSIA IPTNFTISVT TEILPVSMTK TSVDCTMYIC GDSTECSNLL LQYGSFCTQL KRALTGIAVE QDKNTQEVFA QVKQIYKTPP IKYFGGFNFS QILPDPSKPS KRSFIEDLLF NKVTLADAGF IKQYGDCLGD IAARDLICAQ KFKGLTVLPP LLTDEMIAQY TSALLAGTIT SGWTFGAGAA LQIPFAMQMA YRFNGIGVTQ NVLYENQKLI ANQFNSAIGK IQDSLSSTAS ALGKLQDVVN HNAQALNTLV KQLSSKFGAI SSVLNDIFSR LDKVEAEVQI DRLITGRLQS LQTYVTQQLI RAAEIRASAN LAATKMSECV LGQSKRVDFC GKGYHLMSFP QSAPHGVVFL HVTYVPAQEK NFTTAPAICH DGKAHFPREG VFVSNGTHWF VTQRNFYEPQ IITTDNTFVS GNCDVVIGIV NNTVYDPLQP ELDSFKEELD KYFKNHTSPD VDLGDISGIN ASVVNIQKEI DRLNEVAKNL NESLIDLQEL GKYEQYIKWP WYIWLGFIAG LIAIVMVTIM LCCMTSCCSC LKGCCSCGSC CKFDEDDSEP VLKGVKLHYT
NT Sequence
ATGTTTGTTT TTCTTGTTTT ATTGCCACTA GTCTCTAGTC AGTGTGTTAA TCTTACAACC AGAACTCAAT TACCCCCTGC ATACACTAAT TCTTTCACAC GTGGTGTTTA TTACCCTGAC AAAGTTTTCA GATCCTCAGT TTTACATTCA ACTCAGGACT TGTTCTTACC TTTCTTTTCC AATGTTACTT GGTTCCATGT TATCTCTGGG ACCAATGGTA CTAAGAGGTT TGATAACCCT GTCCTACCAT TTAATGATGG TGTTTATTTT GCTTCCATTG AGAAGTCTAA CATAATAAGA GGCTGGATTT TTGGTACTAC TTTAGATTCG AAGACCCAGT CCCTACTTAT TGTTAATAAC GCTACTAATG TTGTTATTAA AGTCTGTGAA TTTCAATTTT GTAATGATCC ATTTTTGGAC CACAAAAACA ACAAAAGTTG GATGGAAAGT GAGTTCAGAG TTTATTCTAG TGCGAATAAT TGCACTTTTG AATATGTCTC TCAGCCTTTT CTTATGGACC TTGAAGGAAA ACAGGGTAAT TTCAAAAATC TTAGGGAATT TGTGTTTAAG AATATTGATG GTTATTTTAA AATATATTCT AAGCACACGC CTATTATAGT GCGTGAGCCA GAAGATCTCC CTCAGGGTTT TTCGGCTTTA GAACCATTGG TAGATTTGCC AATAGGTATT AACATCACTA GGTTTCAAAC TTTACTTGCT TTACATAGAA GTTATTTGAC TCCTGGTGAT TCTTCTTCAG GTTGGACAGC TGGTGCTGCA GCTTATTATG TGGGTTATCT TCAACCTAGG ACTTTTCTAT TAAAATATAA TGAAAATGGA ACCATTACAG ATGCTGTAGA CTGTGCACTT GACCCTCTCT CAGAAACAAA GTGTACGTTG AAATCCTTCA CTGTAGAAAA AGGAATCTAT CAAACTTCTA ACTTTAGAGT CCAACCAACA GAATCTATTG TTAGATTTCC TAATATTACA AACTTGTGCC CTTTTGATGA AGTTTTTAAC GCCACCAGAT TTGCATCTGT TTATGCTTGG AACAGGAAGA GAATCAGCAA CTGTGTTGCT GATTATTCTG TCCTATATAA TCTCGCACCA TTTTTCACTT TTAAGTGTTA TGGAGTGTCT CCTACTAAAT TAAATGATCT CTGCTTTACT AATGTCTATG CAGATTCATT TGTAATTAGA GGTGATGAAG TCAGACAAAT CGCTCCAGGG CAAACTGGAA ATATTGCTGA TTATAATTAT AAATTACCAG ATGATTTTAC AGGCTGCGTT ATAGCTTGGA ATTCTAACAA GCTTGATTCT AAGGTTAGTG GTAATTATAA TTACCTGTAT AGATTGTTTA GGAAGTCTAA TCTCAAACCT TTTGAGAGAG ATATTTCAAC TGAAATCTAT CAGGCCGGTA ACAAACCTTG TAATGGTGTT GCAGGTTTTA ATTGTTACTT TCCTTTACGA TCATATAGTT TCCGACCCAC TTATGGTGTT GGTCACCAAC CATACAGAGT AGTAGTACTT TCTTTTGAAC TTCTACATGC ACCAGCAACT GTTTGTGGAC CTAAAAAGTC TACTAATTTG GTTAAAAACA AATGTGTCAA TTTCAACTTC AATGGTTTAA AAGGCACAGG TGTTCTTACT GAGTCTAACA AAAAGTTTCT GCCTTTCCAA CAATTTGGCA GAGACATTGC TGACACTACT GATGCTGTCC GTGATCCACA GACACTTGAG ATTCTTGACA TTACACCATG TTCTTTTGGT GGTGTCAGTG TTATAACACC AGGAACAAAT ACTTCTAACC AGGTTGCTGT TCTTTATCAG GGTGTTAACT GCACAGAAGT CCCTGTTGCT ATTCATGCAG ATCAACTTAC TCCTACTTGG CGTGTTTATT CTACAGGTTC TAATGTTTTT CAAACACGTG CAGGCTGTTT AATAGGGGCT GAATATGTCA ACAACTCATA TGAGTGTGAC ATACCCATTG GTGCAGGTAT ATGCGCTAGT TATCAGACTC AGACTAAGTC TCATCGGCGG GCACGTAGTG TAGCTAGTCA ATCCATCATT GCCTACACTA TGTCACTTGG TGCAGAAAAT TCAGTTGCTT ACTCTAATAA CTCTATTGCC ATACCCACAA ATTTTACTAT TAGTGTTACC ACAGAAATTC TACCAGTGTC TATGACCAAG ACATCAGTAG ATTGTACAAT GTACATTTGT GGTGATTCAA CTGAATGCAG CAATCTTTTG TTGCAATATG GCAGTTTTTG TACACAATTA AAACGTGCTT TAACTGGAAT AGCTGTTGAA CAAGACAAAA ACACCCAAGA AGTTTTTGCA CAAGTCAAAC AAATTTACAA AACACCACCA ATTAAATATT TTGGTGGTTT TAATTTTTCA CAAATATTAC CAGATCCATC AAAACCAAGC AAGAGGTCAT TTATTGAAGA TCTACTTTTC AACAAAGTGA CACTTGCAGA TGCTGGCTTC ATCAAACAAT ATGGTGATTG CCTTGGTGAT ATTGCTGCTA GAGACCTCAT TTGTGCACAA AAGTTTAAAG GCCTTACTGT TTTGCCACCT TTGCTCACAG ATGAAATGAT TGCTCAATAC ACTTCTGCAC TGTTAGCGGG TACAATCACT TCTGGTTGGA CCTTTGGTGC AGGTGCTGCA TTACAAATAC CATTTGCTAT GCAAATGGCT TATAGGTTTA ATGGTATTGG AGTTACACAG AATGTTCTCT ATGAGAACCA AAAATTGATT GCCAACCAAT TTAATAGTGC TATTGGCAAA ATTCAAGACT CACTTTCTTC CACAGCAAGT GCACTTGGAA AACTTCAAGA TGTGGTCAAC CATAATGCAC AAGCTTTAAA CACGCTTGTT AAACAACTTA GCTCCAAATT TGGTGCAATT TCAAGTGTTT TAAATGATAT CTTTTCACGT CTTGACAAAG TTGAGGCTGA AGTGCAAATT GATAGGTTGA TCACAGGCAG ACTTCAAAGT TTGCAGACAT ATGTGACTCA ACAATTAATT AGAGCTGCAG AAATCAGAGC TTCTGCTAAT CTTGCTGCTA CTAAAATGTC AGAGTGTGTA CTTGGACAAT CAAAAAGAGT TGATTTTTGT GGAAAGGGCT ATCATCTTAT GTCCTTCCCT CAGTCAGCAC CTCATGGTGT AGTCTTCTTG CATGTGACTT ATGTCCCTGC ACAAGAAAAG AACTTCACAA CTGCTCCTGC CATTTGTCAT GATGGAAAAG CACACTTTCC TCGTGAAGGT GTCTTTGTTT CAAATGGCAC ACACTGGTTT GTAACACAAA GGAATTTTTA TGAACCACAA ATCATTACTA CAGACAACAC ATTTGTGTCT GGTAACTGTG ATGTTGTAAT AGGAATTGTC AACAACACAG TTTATGATCC TTTGCAACCT GAATTAGATT CATTCAAGGA GGAGTTAGAT AAATATTTTA AGAATCATAC ATCACCAGAT GTTGATTTAG GTGACATCTC TGGCATTAAT GCTTCAGTTG TAAACATTCA AAAAGAAATT GACCGCCTCA ATGAGGTTGC CAAGAATTTA AATGAATCTC TCATCGATCT CCAAGAACTT GGAAAGTATG AGCAGTATAT AAAATGGCCA TGGTACATTT GGCTAGGTTT TATAGCTGGC TTGATTGCCA TAGTAATGGT GACAATTATG CTTTGCTGTA TGACCAGTTG CTGTAGTTGT CTCAAGGGCT GTTGTTCTTG TGGATCCTGC TGCAAATTTG ATGAAGACGA CTCTGAGCCA GTGCTCAAAG GAGTCAAATT ACATTACACA