BehuA.18655.a

Spike glycoprotein (S)

CENTER ID: BehuA.18655.a
ORGANISM: Betacoronavirus Human coronavirus HKU1 isolate N1
ASSOCIATED DISEASE:
CURRENT STATUS: in PDB
COMMUNITY REQUEST: False
NIH RISK GROUP: 2
SELECT AGENT: False
NIH PRIORITY
pathogens category:		 IIIC

Ordering Clones & Proteins

If there are materials available for this target, they will be listed below. Materials can be ordered from SSGCID using the button in the "order material" column. Clicking the button will add the material to a virtual cart. You may order multiple materials at a time at no cost to you, as this contract is funded by NIAID. When you are ready to place your order, click the "Place Order" link which will appear in the top right corner of the page after you place your first item in your cart.

Structures

8VGT
DEPOSITED: 12/27/2023
DETERMINATION: CryoEM
CLONE: BehuA.18655.a.K21.GE45599
PROTEIN: BehuA.18655.a.K21.PE00079

Publications by SSGCID

Human coronavirus HKU1 recognition of the TMPRSS2 host receptor
Tortorici MA, Veesler D, Park YJ, Telenti A, McCallum M, Addetia A, Sprouse K, Stewart C, Brown J, Gibson C, Wong E, Ieven M
Cell - 2024
volume 187, issue 16, pages 4231-4245
PMID: 38964328
PDB: 8VGT

External Resources

RESOURCE REFERENCE ID
UniProt: Q5MQD0

Sequences

These sequences are the native gene sequence; sequences of constructs derived from these sequences may differ due to codon optimization or other protocols. To find the specific sequence of any material you may have ordered, click on the "info" button next to the name of that material.
AA Sequence
MLLIIFILPT TLAVIGDFNC TNFAINDLNT TVPRISEYVV DVSYGLGTYY ILDRVYLNTT ILFTGYFPKS GANFRDLSLK GTTYLSTLWY QKPFLSDFNN GIFSRVKNTK LYVNKTLYSE FSTIVIGSVF INNSYTIVVQ PHNGVLEITA CQYTMCEYPH TICKSKGSSR NESWHFDKSE PLCLFKKNFT YNVSTDWLYF HFYQERGTFY AYYADSGMPT TFLFSLYLGT LLSHYYVLPL TCNAISSNTD NETLQYWVTP LSKRQYLLKF DNRGVITNAV DCSSSFFSEI QCKTKSLLPN TGVYDLSGFT VKPVATVHRR IPDLPDCDID KWLNNFNVPS PLNWERKIFS NCNFNLSTLL RLVHTDSFSC NNFDESKIYG SCFKSIVLDK FAIPNSRRSD LQLGSSGFLQ SSNYKIDTTS SSCQLYYSLP AINVTINNYN PSSWNRRYGF NNFNLSSHSV VYSRYCFSVN NTFCPCAKPS FASSCKSHKP PSASCPIGTN YRSCESTTVL DHTDWCRCSC LPDPITAYDP RSCSQKKSLV GVGEHCAGFG VDEEKCGVLD GSYNVSCLCS TDAFLGWSYD TCVSNNRCNI FSNFILNGIN SGTTCSNDLL QPNTEVFTDV CVDYDLYGIT GQGIFKEVSA VYYNSWQNLL YDSNGNIIGF KDFVTNKTYN IFPCYAGRVS AAFHQNASSL ALLYRNLKCS YVLNNISLTT QPYFDSYLGC VFNADNLTDY SVSSCALRMG SGFCVDYNSP SSSSSRRKRR SISASYRFVT FEPFNVSFVN DSIESVGGLY EIKIPTNFTI VGQEEFIQTN SPKVTIDCSL FVCSNYAACH DLLSEYGTFC DNINSILDEV NGLLDTTQLH VADTLMQGVT LSSNLNTNLH FDVDNINFKS LVGCLGPHCG SSSRSFFEDL LFDKVKLSDV GFVEAYNNCT GGSEIRDLLC VQSFNGIKVL PPILSESQIS GYTTAATVAA MFPPWSAAAG IPFSLNVQYR INGLGVTMDV LNKNQKLIAT AFNNALLSIQ NGFSATNSAL AKIQSVVNSN AQALNSLLQQ LFNKFGAISS SLQEILSRLD ALEAQVQIDR LINGRLTALN AYVSQQLSDI SLVKFGAALA MEKVNECVKS QSPRINFCGN GNHILSLVQN APYGLLFMHF SYKPISFKTV LVSPGLCISG DVGIAPKQGY FIKHNDHWMF TGSSYYYPEP ISDKNVVFMN TCSVNFTKAP LVYLNHSVPK LSDFESELSH WFKNQTSIAP NLTLNLHTIN ATFLDLYYEM NLIQESIKSL NNSYINLKDI GTYEMYVKWP WYVWLLISFS FIIFLVLLFF ICCCTGCGSA CFSKCHNCCD EYGGHHDFVI KTSHDD
NT Sequence
ATGTTATTAA TTATTTTTAT TTTGCCTACA ACATTAGCTG TTATAGGTGA TTTTAATTGT ACTAATTTTG CTATTAATGA TTTAAACACC ACAGTTCCTC GCATAAGTGA GTATGTTGTG GATGTTTCTT ATGGTTTGGG TACATATTAT ATACTTGATC GTGTTTATTT AAATACTACT ATATTATTTA CTGGTTATTT CCCTAAATCT GGTGCCAATT TTAGGGATCT ATCTTTAAAA GGTACTACAT ATTTGAGTAC TCTTTGGTAT CAGAAACCCT TTTTATCTGA TTTTAATAAT GGTATTTTTT CTAGAGTTAA GAATACTAAG TTGTATGTTA ATAAAACTTT GTATAGTGAG TTTAGTACTA TAGTTATAGG TAGTGTTTTT ATTAACAACT CTTATACTAT TGTTGTTCAA CCTCATAATG GTGTTTTGGA GATTACAGCT TGTCAATACA CTATGTGTGA GTATCCTCAT ACTATTTGTA AATCTAAAGG TAGTTCTCGT AATGAATCTT GGCATTTTGA TAAATCTGAA CCTTTGTGTC TGTTCAAGAA AAATTTTACT TATAATGTTT CTACAGATTG GTTGTATTTT CATTTTTATC AAGAACGTGG CACTTTTTAT GCTTATTATG CTGATTCTGG CATGCCTACT ACTTTTTTAT TTAGTTTGTA TCTTGGTACT CTTTTATCTC ATTATTATGT TTTGCCTTTG ACTTGTAATG CTATATCTTC TAATACTGAT AATGAGACTT TACAATATTG GGTCACACCT TTGTCTAAAC GCCAATATCT TCTTAAATTT GACAACCGTG GTGTTATTAC TAATGCTGTT GATTGTTCTA GTAGTTTCTT TAGCGAGATT CAATGTAAAA CTAAATCTTT ATTACCTAAT ACTGGTGTTT ATGACTTATC TGGTTTTACT GTTAAGCCTG TTGCAACTGT ACATCGTCGT ATTCCTGATT TACCTGATTG TGACATTGAT AAATGGCTTA ACAATTTTAA TGTACCCTCA CCTCTTAATT GGGAACGTAA AATTTTTTCT AATTGCAACT TTAATTTGAG TACTTTGCTT CGTTTAGTTC ATACTGATTC TTTTTCTTGT AATAATTTTG ATGAATCTAA GATATATGGT AGTTGTTTTA AGAGTATTGT TTTAGATAAA TTTGCCATAC CCAACTCCAG ACGATCTGAT TTGCAGTTGG GCAGTTCTGG TTTTCTGCAA TCTTCTAATT ATAAAATTGA CACTACTTCT AGTTCTTGTC AATTGTATTA TAGTTTGCCT GCAATTAATG TTACTATTAA TAATTATAAT CCTTCTTCTT GGAATAGAAG GTATGGTTTT AATAATTTTA ATTTGAGCTC TCATAGTGTT GTTTACTCAC GTTATTGTTT TTCTGTTAAT AATACTTTTT GTCCTTGTGC TAAACCTTCT TTTGCTTCAA GTTGCAAGAG TCATAAACCA CCTTCTGCTT CCTGTCCTAT TGGTACTAAT TATCGTTCTT GTGAGAGTAC TACTGTACTC GACCACACTG ACTGGTGTAG GTGTTCTTGT TTACCTGATC CTATAACTGC TTATGACCCT AGGTCTTGTT CTCAAAAAAA GTCTCTGGTT GGTGTTGGTG AACATTGTGC AGGGTTCGGT GTTGATGAAG AAAAGTGTGG TGTATTGGAT GGATCATATA ATGTTTCTTG TCTTTGTAGT ACTGATGCCT TTCTAGGTTG GTCTTATGAC ACTTGCGTCA GTAACAACCG TTGTAATATT TTTTCTAATT TTATTTTAAA TGGTATCAAT AGTGGTACCA CTTGTTCTAA TGATTTATTG CAGCCTAATA CTGAAGTTTT TACTGATGTT TGTGTTGATT ACGACCTTTA TGGTATTACA GGACAAGGTA TTTTTAAAGA AGTTTCTGCT GTTTATTATA ATAGTTGGCA AAATCTTTTG TATGATTCTA ATGGCAACAT TATTGGTTTT AAAGATTTTG TTACTAATAA AACATATAAT ATTTTCCCTT GTTATGCAGG AAGAGTTTCT GCTGCTTTTC ATCAAAATGC TTCCTCTTTG GCTTTACTTT ATCGTAATTT AAAATGTAGC TATGTTTTGA ATAATATTTC TTTAACTACT CAGCCATATT TTGATAGTTA TCTTGGTTGC GTTTTTAATG CTGATAATTT AACTGATTAT TCTGTTTCTT CTTGTGCTCT TCGCATGGGT AGTGGTTTTT GTGTTGATTA TAACTCACCT TCTTCTTCCT CTTCGCGTCG TAAACGTAGA AGTATTTCTG CTTCTTATCG TTTTGTTACT TTTGAACCCT TTAATGTCAG TTTTGTTAAT GACAGTATTG AGTCTGTGGG TGGTCTTTAT GAGATCAAAA TTCCCACTAA CTTTACTATA GTTGGTCAAG AGGAATTTAT TCAAACTAAT TCTCCTAAAG TTACTATTGA TTGTTCTTTA TTTGTCTGTT CTAATTATGC AGCTTGCCAT GACTTATTGT CAGAGTATGG CACTTTTTGT GATAATATTA ATAGTATTTT AGATGAAGTT AATGGTTTAC TTGATACTAC TCAATTGCAT GTAGCTGATA CTCTTATGCA AGGTGTCACA CTTAGCTCCA ATCTTAATAC TAATTTGCAT TTTGATGTTG ATAATATTAA TTTTAAATCC CTAGTTGGAT GTTTAGGTCC ACACTGCGGT TCTTCTTCTC GTTCTTTTTT TGAAGATTTA TTGTTTGACA AAGTTAAACT TTCAGATGTT GGTTTTGTTG AAGCTTATAA CAATTGTACT GGTGGTAGTG AAATTAGAGA TCTTCTTTGT GTACAATCCT TTAATGGTAT TAAAGTTTTG CCTCCTATTT TGTCTGAATC TCAAATTTCT GGTTACACCA CAGCCGCTAC TGTTGCTGCT ATGTTTCCAC CATGGTCAGC AGCAGCTGGC ATACCATTTT CTCTTAATGT ACAATATAGA ATTAATGGTT TGGGTGTTAC TATGGATGTT CTTAATAAAA ATCAAAAGTT GATAGCTACT GCTTTTAATA ATGCTCTTCT TTCTATTCAG AATGGTTTTA GTGCTACCAA CTCTGCACTT GCTAAAATAC AAAGTGTTGT TAATTCTAAT GCTCAAGCAC TTAATAGTTT GTTACAGCAA TTATTTAATA AATTTGGTGC AATTAGTTCT TCTTTACAAG AAATTTTATC TCGTCTCGAT GCTTTAGAGG CTCAGGTTCA GATTGATAGG CTTATTAATG GTCGTTTAAC TGCTTTAAAT GCTTATGTCT CTCAACAGCT TAGTGATATT TCTCTTGTAA AATTTGGTGC TGCTTTAGCT ATGGAGAAGG TTAATGAGTG TGTTAAAAGT CAATCTCCTC GTATTAATTT TTGTGGTAAT GGTAATCATA TTTTGTCATT AGTTCAAAAT GCTCCTTATG GTTTGTTGTT TATGCATTTT AGTTATAAAC CTATTTCTTT TAAAACTGTT TTAGTAAGTC CTGGTTTGTG TATATCAGGT GATGTAGGTA TTGCACCTAA ACAAGGGTAT TTTATTAAAC ATAATGATCA TTGGATGTTC ACTGGTAGTT CTTACTATTA TCCTGAACCA ATTTCAGATA AAAATGTTGT TTTTATGAAT ACTTGTTCTG TTAATTTTAC TAAAGCGCCT CTTGTTTATT TGAATCATTC TGTACCAAAA TTGTCTGATT TTGAATCTGA GTTATCTCAT TGGTTTAAAA ATCAAACATC CATTGCGCCT AATTTGACTT TAAATCTTCA TACTATTAAT GCTACTTTTT TAGATTTGTA TTATGAGATG AATCTTATTC AAGAGTCTAT TAAGTCTTTG AATAATAGTT ATATCAATCT TAAAGATATA GGTACATATG AAATGTATGT AAAATGGCCT TGGTATGTTT GGCTACTAAT TTCTTTTTCA TTTATAATAT TCCTTGTATT GCTCTTTTTT ATATGTTGTT GTACTGGTTG TGGTTCTGCA TGTTTTAGTA AATGTCATAA TTGTTGTGAT GAGTATGGTG GTCATCATGA TTTTGTTATC AAAACATCTC ATGATGAT