(Required) Choose the most relevant option:
Known drug target – The gene product is the target of a drug which is currently on the market or in development. Minimally, inhibitors of the target will have been shown to block cell growth in the genus/species listed.
Potential drug target – An ortholog of a known drug target, an essential gene or a homolog of an essential gene.
Targets associated with virulence and/or pathogenesis- A gene product associated with pathogen adhesion, colonization, invasion, immune response inhibition or toxicity of the host cells.
Vaccine candidate- A gene product identified as a vaccine candidate.
Targets involved in drug resistance- The gene product is confirmed or suggested to be involved (directly or indirectly) in drug-target binding, drug degradation or drug removal all of which result in evolution over time of drug resistance.
Targets showing phylogenetic evidence for essentiality, virulence or pathogenesis- Targets for which orthologues present in a pathogenic species/strain and absent in a non-pathogenic species/strain.
Targets associated with innate immunity- Human proteins associated with non-adaptive immune mechanisms that recognize, and respond to, microorganisms, microbial products and antigens.
Marker of infection- A biomarker, antigen or other protein used to detect pathogen infection.
Targets of other biological interest- targets falling outside the categories described above.
Unknown